New Studies Show the Downside Of Cancer Screening

Recent years have seen a rise in encouragement for cancer screenings, but a number of studies have reminded physicians and their patients of the old saying about free lunches.

That is, nothing good comes without a cost.

Two studies released Monday -- one looking at prostate cancer and the other at breast cancer -- appearing in the Journal of the National Cancer Institute, show that increased screening brings false positives and the costs of emotional anguish and sometimes unnecessary treatment.

VIDEO: Results from prostate and breast cancer tests may lead to unnecessary treatment.
null

"The fact that it is a surprise to so many physicians and so many patients is a symptom of the debate taking place now regarding health care reform," said Dr. Thomas Schwenk, a family physician with the University of Michigan, commenting on the prostate cancer study. "The American approach to medical care is to always do more, irrespective of whether it has any value, and even in the face of data showing that doing more causes harm."

While the prostate cancer study, which utilized data from the National Cancer Institute (not affiliated with the journal that published the study), and the breast cancer study, which used data from women being screened in the province of Ontario, Canada, were in two different cancers in two different populations, both studies came to similar conclusions; in short, a lot of patients were receiving unnecessary treatments.

VIDEO: Coping With Prostate Cancer
null

In the breast cancer screening study, women in Ontario were given a clinical breast exam in addition to mammography.

"I think that women should be informed of the benefits and limitations if they have a clinical breast exam in addition to mammography," said Anna Chiarelli, an epidemiologist at the University of Toronto and one of the authors of the breast screening study. "For every additional cancer found there were 55 false positives."

Meanwhile, according to the prostate cancer study's authors, between the years 1986 and 2005, 1 million "additional" men were diagnosed with prostate cancer.

"Given the considerable time that has passed since PSA screening began, most of this excess incidence must represent overdiagnosis," concluded Dr. H. Gilbert Welch, professor of medicine and community and family medicine at Dartmouth Medical School and Dr. Peter C. Albertsen, chief and program director of the division of urology at the University of Connecticut Health Center.

"It is of note that countries that do not have widespread screening as a policy have seen some declines in prostate mortality without the harm of frequent overdiagnosis," said Dr. Otis Brawley of the American Cancer Society in a related editorial.

Even If a Free Lunch Is Not Free, It's Still Lunch

While acknowledging the costs of false positives in cancer screenings, physicians said it is important not to look past the benefits those screenings bring as well.

"There is no question that prostate cancer is being over-detected and over-treated today," said Dr. Peter Scardino, chair of the department of surgery at Memorial Sloan-Kettering Cancer Center. "It is, however, a serious mistake to suggest that PSA cannot detect many potentially lethal cancers at a time when they can be cured with surgery and radiation. While there is some argument about the benefits of PSA screening, prostate cancer mortality rates have declined by 50 percent over the last 15 years."

Dr. Patrick Walsh, a professor of urology at Johns Hopkins, argued that the prostate study is deeply flawed.

Page
  • 1
  • |
  • 2
  • |
  • 3
null
Join the Discussion
You are using an outdated version of Internet Explorer. Please click here to upgrade your browser in order to comment.
blog comments powered by Disqus
 
You Might Also Like...