Do We Know Of Any Genes That Predispose Someone To Developing Osteoarthritis?

Share
Copy

Question: Do we know of any genes that predispose someone to developing osteoarthritis?

Answer: One of the more exciting things that's been going on in the research in osteoarthritis recently is trying to determine whether or not there's a genetic predisposition. It all started with a family of people in Toledo, Ohio, that had everybody in the family had osteoarthritis. And what they did is they isolated the gene and found out that one of the proteins that was developing that binds the tissues together was abnormal. So they did find a specific genetic defect in that family. Since that time, there have been several additional families and additional defects have been identified. But the overall genetic predisposition has not been cleanly defined yet. There are some very large studies going on, both in the United Kingdom and in the United States, that are looking at genetics and trying to find out what the genetic predisposition is.

Next: How Does Family History Affect My Risk Of Developing Osteoarthritis?

null

Previous: Can Hormones Affect My Risk Of Developing Osteoarthritis?
-- This embed didnt make it to copy for story id = 4566576. -- This embed didnt make it to copy for story id = 4566576. -- This embed didnt make it to copy for story id = 4566576.
Join the Discussion
You are using an outdated version of Internet Explorer. Please click here to upgrade your browser in order to comment.
blog comments powered by Disqus
 
You Might Also Like...
See It, Share It
PHOTO: U.S. Customs and Border Protection officers at the George Bush Intercontinental Airport in Houston stopped a would be smuggler from bringing nearly 7 ounces of cocaine into the country in tamales, Aug. 22, 2014.
U.S. Customs and Border Protection
In this image from video posted on Facebook, courtesy of the George W. Bush Presidential Center, former President George W. Bush participates in the ice bucket challenge with the help of his wife, Laura Bush, in Kennebunkport, Maine.
(Courtesy George W. Bush Presidential Center/AP)
Real Housewife Phaedra Parks Lists Home in Suburban Atlanta
Real Housewives of Atlanta star, Phaedra Parks, has listed her 4,000-square-foot home with 5 bedrooms and 6 baths for $340,900.