In an interview with Larry King on CNN, Griffith, 50, said doctors gave out painkillers regularly. She was taking Percocet and Norcal "to ease the pain. And also because I was addicted."
Doctors say these kinds of addictions are on the increase. And for celebrities, the risk can be even greater.
"They probably have more easy access to certain kinds of medications, without seeing a physician," said Dr. Benoy Benny, assistant professor of physical medicine and rehabilitation at Baylor College of Medicine in Houston. "One of the things we can learn is that celebrities are not perfect. … They go through tough times just like other people."
Griffith has toned down her "wild child" ways since her marriage to Spanish actor Antonio Banderas.
Taylor may be best known for her violet eyes and string of husbands, but the two-time Oscar winner suffered through much of the glamour of old Hollywood.
Taylor was born with scoliosis, which can cause an unnatural curvature of the spine, and she has suffered back pain for years.
"My back [has] been chronically bad since I was a teenager," Taylor told Larry King on CNN.
In addition, the actress has been addicted to alcohol, painkillers and sleeping pills. And she also weathered a near-fatal bout of pneumonia.
Taylor's experiences with chronic pain helped fuel her philanthropic drive. As the co-founder and co-chairman of the American Foundation for AIDS Research, Taylor has raised more than $80 million since it was founded in 1985.
And the iconic star of "Cleopatra" and "Cat on a Hot Tin Roof" has not let the pain get the better of her.
"You don't, if you want to go on functioning," Taylor said. "You grin and bear it, and try and get as much sleep as you can, because sleep is a great healer, I find."
Favre is a three-time MVP winner, two-time Super Bowl veteran and the starting quarterback for the Green Bay Packers.
But his glittering, 17-season career in the National Football League was dimmed by chronic pain, brought about by bone spurs growing on his left ankle. Favre twice had surgery on his ankle, once in 1995, and again in 2007.
Favre suffers chronic pain from his condition, but he said that he rarely takes medication for it and that the pain is tolerable.
Even though professional athletes can push themselves to physical limits most people cannot, Favre's "suck it up and go attitude," may be harming him more than it cheers millions of his fans.
"There are certain situations where you can play through the pain," Chisholm noted. "But there is always something to be lost in the future."
Favre may have a tough-man reputation, but the line between playing for love of the game, and playing to the fans, can be fine in professional sports.
"[Professional athletes] are kind of held to this higher standard, and are not allowed to have the problems everyone else has," Chisholm said. "We want them to be Superman. We want Brett Favre to be that guy who wins the game at the end, and gets knocked down 20 million times, and keeps getting up."
In her immortal role as Jenny Handley in the 1979 comedy "10," Derek stole the screen as the proverbial carefree "perfect" beauty.
But Derek's real-life battle with pain has been far from a carefree endeavor. She says that years of horseback riding have weakened her back — even contributing to a painful herniated disc.