Despite touting modest successes after three days of meetings, Obama allowed that he feels ambivalent toward these large summits and thinks that their shape will evolve over the next several years.
"The one thing I will be looking forward to is fewer summit meetings. Because as you said, I've only been in office six months now, and there're been a lot of these, and I think that there is a possibility of streamlining them and making them more effective," he said.
Obama is the host of the next major international summit -- the follow-up meeting on the global economic crisis with the G-20 nations in Pittsburgh in September.
He acknowledged that it is difficult to determine who to include in these global summits and that every nation wants a seat at an exclusive table.
"One point that I did make in the meeting is what I've noticed is that everybody wants the smallest possible group, smallest possible organization that includes them," he said. "So if they're the 21st largest nation in the world, then they want the G-21 -- and think it's highly unfair if they've been cut out."
Ghana is the final stop on Obama's six-day trip. There, he will meet with newly elected President John Atta Mills and deliver a speech to members of parliament.
The president and first lady will visit a hospital in Accra that focuses on maternal and child health care and, weather permitting, are scheduled to take a helicopter to tour the Cape Coast Castle, an old slave fort where hundreds of thousands of Africans were held before being put on slave ships.
White House officials said the Ghana stop is meant to show that Africa is not a "separate sphere" but a key part of the administration's overall foreign policy. The White House chose Ghana over other African nations, including Kenya, where Obama's father was from, to showcase a successful African democracy. Ghana has held peaceful democratic elections, including Mills' election earlier this year.
"It's an admirable example of strong, democratic governance, vibrant civil society," said senior White House director for African affairs Michelle Gavin. "They've made tremendous development progress over the past decade, as well. There's much to admire and to sort of hold up something of a counter to what one often hears about Africa, sort of a litany of crises and conflict. It's certainly not the case in Ghana."
Ghanaians are eagerly awaiting Obama's visit, but there is some grumbling that the trip is too short and the president is not holding a large public event in Accra, as former presidents Bill Clinton and George W. Bush did on trips to Ghana.
"I do not believe that there is a way in which we could ever fulfill or assuage the desires of those in Ghana or on the continent on one stop with a public stop," said White House Press Secretary Robert Gibbs.
There will be a departure ceremony at the airport in Accra for thousands of invited guests, but it is not open to the public.
ABC News' Jon Garcia and Phoebe Natanson contributed to this report.