The Obama campaign launched an anti-smear Web site last week to combat those false rumors and others about the candidate.
Asked by Joy Behar whether she thought Clinton had been the victim of sexism in the media, Obama agreed.
"People aren't used to strong women," she said, "We don't even know what to say about them."
Obama credited Clinton for "putting cracks" in the proverbial glass ceiling.
It's only when women like her take the hits and it's painful, it's hurtful, but she' s taking them so that my girls, when they come along, won't have to feel it as badly," she said.
Walters asked why she was reticent early on about her husband's presidential bid. Obama candidly spoke about not wanting the give up her husband to national politics.
"I was like 'please, don't do this,'" she said. "I didn't want Barack to go into politics because I thought politics was a mean business. I knew this man that I loved, he was sweet, empathetic."
But when she though about it as a voter and a mother, she said, she knew her husband was the right choice for the country.
Early in the show, as if to diffuse any tension between Obama and Elisabeth Hasselbeck, a vocal Republican, co-host Whoopi Goldberg said on the air, "Okay you two, no mor hair-pulling!"
"I'm sorry," Obama deadpanned. "We're through," Hasselbeck said, smiling as Obama.
Later, during a commercial break, Hasselbeck broke into tears while explaining to audience members that she is sad to be leaving her baby boy, Taylor, for the first time next week to tape the show in Las Vegas next week.
The potential first lady appeared to briefly console her as all of the ladies sat on the couch in preparation for a group interview of celebrity guest Matthew Broderick.
Obama looked over at a teary Hasselbeck and appeared to whisper to her and fellow co-host Sherri Shepherd, "Everything okay?"
On the air today, Hasselbeck said it was ridiculous for people to anticipate a "girl fight" between herself and Michelle Obama.
"We must be enemies because we disagree politically?" Hasselbeck asked rhetorically.
Hasselbeck, who supports the Iraq war and spoke at the 2004 Republican Convention, grilled Barack Obama during his appearance in March over his association with Rev. Jeremiah Wright.
On the air, Obama said of Hasselbeck: "This girl is solid, she's got great kids, she's funny."
Reviews of Obama's 'View' performance from audience members were mixed.
As the show was ending, Janet Brown, 70, of New Jersey leaned over to her friend and whispered, "She rocks, I have a whole new outlook on her."
"She's not going to be president," responded Eileen Curtis, 74.
Kelly Robinson, wife of Michelle's brother Craig Robinson, told ABC News her sister-in-law's 'View' appearance was a good way to see her.
"She's doing terrific," Robinson told ABC News between segments.
Michelle Obama is viewed more favorably by likely voters than Cindy McCain, 48 percent to 39 percent, according to a recent ABC News/Washington Post poll. But while Obama leads in favorability, many voters say they haven't formed an opinion yet of McCain, and slightly more voters also view Obama unfavorably — 29 percent vs. McCain's 25 percent.
Scrutiny of the potential first ladies was evident among audience members waiting to get into the live show.
"I think she's wonderful," Veronica Deas, 45, said of Michelle Obama.