'He' Becomes 'She': Husband's Transformation Into a Woman

Chloe Prince: 'Everything's Changing'

For reasons unknown to Rene, Ted became distant and started to pay more attention to projects around the house than to his pregnant wife. At a time when many couples feel renewed intimacy, Ted had a very different emotion: jealousy.

"I wanted to be the one there carrying this baby, you know," said Chloe. "And I wanted to feel that life inside me."

By the summer of 2003, life had settled into a reliable rhythm for Ted and Rene. Ted's stash of women's clothing in closets and hidden boxes had grown, but not significantly. Although still confused, Ted was able to occupy idle hands with work and the birth of a second son, Barry.

"We became pregnant with Logan just six months after our marriage," said Chloe. "And within two years, we had two children, [a] house, [a] mortgage. Everything's changing."

A Bee Sting With Big Consequences

One day, while out on a motorcycle ride, Ted was stung several times by a bee. He was severely allergic to bee stings, so Rene rushed him to the hospital.

"They start putting me on IVs of epinephrine and different hormones, trying to counter and stop this bee sting reaction," Chloe said.

A blood test at the hospital led to an endocrinologist and a diagnosis that Chloe said explained why she had felt so different her whole life.

"They sat me down and they said, 'Are you aware of having Klinefelter's syndrome?' And I [said] 'No, what is that? Never heard of [it].'"

Klinefelter's syndrome is one of the most common chromosomal abnormalities in humans. Normally, a male is born with XY chromosomes and a female XX, but an estimated one in every 500 boys is born XXY. One of the main side effects of Klinefelter's syndrome is a much lower level of testosterone than the average male.

The news of his medical condition was a moment of clarity for Ted, who for so long had struggled with gender identity issues.

"The veil was off," said Chloe. "I was like, this is why, you know, I tap dance like a little cat on the fence of the gender line -- why I can't commit to either side. Appearance-wise, I look like every other male, but on a DNA-chromosomal scale, I was neither."

Chloe says the doctors told them that the severity of the sting had essentially reset Ted's endocrine system, according to Chloe. Gradually, his body started to change. Initially, Rene thought Ted was gaining weight, but they knew something else was going on when he started developing breasts.

"I had muscular arms, [but] all that started to change with Klinefelter's shifting the dynamics of my endocrine system. I could see that the fat density in my face and my body, the softness of my skin, my muscular features were all changing at that point," Chloe said.

With an actual medical diagnosis to help explain why he had felt different his whole life, Ted felt free to express his true identity.

"I wanted to physically align my body in appearance with how I felt inside. I wanted to be authentically myself -- which was female. I didn't feel like I needed to prove myself anymore to my father, to the world, to my mom. I didn't need to be a man."

But for Rene, it was incredibly painful to watch the man she loved disappear.

Chloe Prince: 'Not All About Yourself'

"Rene saw it on a daily basis," said Chloe. "Each day, it was another death for her because it would be something -- I would start adding earrings or I started adding a woman's ring on my finger."

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