"While Rob may not have been my initial choice for commissioner, the conclusion of a very good process was to name Rob as the person best positioned to help baseball endure and grow even stronger for the next generation of fans," Reinsdorf said in a statement. "Today's decision was reached by 30 owners voting separately but speaking, in the end, with one voice."
Werner, who made his career as a television executive, was preferred by those who wanted an owner to follow Selig, who was the longtime head of the Brewers when he took over MLB.
"I think the last two days have been productive because we've been able to share a number of ideas about the game and how to improve it and modernize it," Werner said. "I think that Rob agrees with many of the ideas that I espoused, and I am very confident that we are going to see some things, such as improved pace of play."
Brosnan quit the race when it became apparent he likely had one vote: Cincinnati.
"I cared too much about the game and really wanted the process to be as efficient as it could be," he said.
Manfred has been chief operating officer since September 2013, a role in which he reports directly to Selig and oversees functions such as labor relations, baseball operations, finance, administration and club governance.
Manfred had spent the previous 15 years as MLB's executive vice president of labor relations and human resources, and received an expanded role of executive vice president of economics and league affairs in 2012. He was the point man in negotiating the past three labor agreements, with all three negotiated without a work stoppage for the first time since the rise of the MLB Players Association in the 1970s. He also helped lead negotiations for the first joint drug agreement that was instituted in 2002 and has been strengthened repeatedly.
Manfred started with baseball in 1987 as a lawyer with Morgan, Lewis & Bockius who assisted in collective bargaining.
Manfred has been to Selig what Silver was to Stern -- a longtime trusted aide who negotiated labor deals, handled crises such as the Los Angeles Dodgers' bankruptcy saga and was intimately involved in major issues ranging from drug testing to revenue sharing. Manfred has taken criticism in recent months, however, for some of the methods baseball employed in its controversial Biogenesis investigation.
"There is no doubt in my mind he has the training, the temperament, the experience to be a very successful commissioner," Selig said, "and I have justifiably very high expectations."
Manfred -- whose term was not specified but is expected to receive a three-year contract, according to multiple reports -- grew up in Rome, New York, about an hour's drive from the Hall of Fame in Cooperstown. He must address issues that include decreased interest in baseball among younger people and an average game time that has stretched to 3:03, up 30 minutes from 1981. And he will be leading an opinionated group of multimillionaires and billionaires.
"I think some of Rob's greatest attributes are his ability to reach consensus," said St. Louis Cardinals owner Bill DeWitt Jr., who chaired the committee that picked the three candidates.