Want to Get Smarter? Eat Dirt

A common soil bacteria helps mice learn tasks, ease anxiety, new research shows.

ByABC News
June 8, 2010, 4:28 PM

June 9, 2010 — -- A walk through the woods may do wonders for easing anxiety and learning new tasks, according to new research.

Microbiologists at The Sage Colleges in Troy, New York, found that feeding mice a bacteria that is commonly found in soil had a powerful effect on how well they figured out how to get through a complex maze. It also eased their anxiety.

"We were very surprised" at how much improvement the bacteria, Mycobacterium vaccae, made in the performance of mice that got the bacteria compared to mice that didn't, researcher Dorothy Matthews said in a telephone interview.

Matthews and a colleague, Susan Jenks, presented their results during a recent meeting of the American Society for Microbiology in San Diego.

The experimental mice found their way through the maze in half the time it took for a control group that did not receive the bacteria, Matthews said.

And it wasn't a simple task, she added. The mice had to make eight decisions about which pathway to follow, "so it was complicated. If I was going to a place where I needed to make eight decisions about turning left or right, I would consider that a pretty high order task," she said.

So does that mean we all need to start eating mud pies? Not really, she added. The bacteria is so common that we are probably exposed to a sufficient dose every time we walk down a path, or work in the garden, or simply dig around in the dirt.

The research builds on previous work published by others in England in 2007. That research showed that the bacteria injected into mice stimulated growth of some neurons in the brain that resulted in increased levels of serotonin and decreased anxiety.

"The notion that a bacterium that could influence the function of the brain in a positive way was fascinating to me," Matthews said. Serotonin is known to stimulate learning, and the researchers wanted to know how much it helped mice in a controlled lab experiment.

Twenty immature 38-day-old-mice were recruited for the task. They were given a couple of weeks to mature and feel comfortable in their new home. The mice learned that if they found their way to the end of a maze, they were rewarded with slab of bread with a bit of peanut butter.