"You will bankrupt the country if this bill passes!" Rove insisted.
Plouffe responded with another jab: "Karl and the Republicans have zero credibility -- about as much credibility as the country of Greece does to talk about fiscal responsibility."
Rove, brandishing a white board with health care cost figures, interrupted: "For God's sake, will you stop throwing around epithets and deal with the facts for once, David!"
Plouffe, rolling his eyes, responded: "Let's put the fanciful chart away ..."
Before he could finish, Rove interrupted: "This is not a fanciful chart, deal with the chart!"
Plouffe said Democrats were helping to get the country back on track and address big issues such as health care and that "the Republican Party, for the most part, is not lifting an oar to help row us ... " Plouffe said.
"That's bunk!" Rove interjected. "Republicans have offered a positive alternative on health care and you didn't bother to have one meeting between March 5 of 2009 and February 25 of 2010 to discuss how the White House could involve some of those Republican ideas in the bill. Don't give us that bunk," Rove said.
2010 is looking brighter for Democrats than the pundits would have people believe, Plouffe said, and that the president will be out there campaigning not just for Democrats who support the health care bill, but for ones who do not.
"For a variety of reasons -- we've got a tough economy, we've run a lot of races so we've got a lot to defend -- we're going to have a tough election," Plouffe said. "But I think our election outcome in 2010 can be a lot better than a lot of the pundits think by passing health care."
Plouffe said he looked forward to a good debate this fall.
"It's going to be about health care reform, and I think that is a debate we are positioned to win," he said.
Guest host Jonathan Karl pressed Plouffe: Would the president campaign for representatives who voted "no" on health care reform?
"Of course," Plouffe said. "I'm sure he'll be out there helping people who vote 'yes' on this, who vote 'no' on this."