"She went into medicine because she wanted to help people as best she could," he said. "While she was a great achiever, she really showed that the great achievement she had was really to be more competent and passionate about caring for the sick ... research that she felt hopefully will bring cures."
Today's funeral comes less than a week after Le was memorialized at a service on Long Island where her fiancé, Jonathan Widawsky, lives. Le's body was found the day she and Widawsky, who met at the University of Rochester, were to be married.
Widawsky is studying physics as a graduate student at Columbia University.
In a statement released to Yale University Friday, Le's family said the 24-year-old will be "profoundly missed."
"Annie was loved by everyone who knew her and special to all those who came in contact with her," the statement read. "She was a kind-hearted human being, who was devoted to her family and friends, always sacrificing her time to help others. Her laughter was infectious and her goodness was ingenuous."
Yale University announced that the school will hold its own memorial service Oct. 12 and has established a scholarship fund in Le's name.
According to Yale University's Web site, Le, who graduated at the top of her high school class in 2003, joined the Yale student body in 2007 as a graduate pharmacology student and was studying how fatty acids regulate an enzyme believed to be involved in the development of metabolic disease.
She would have earned her doctorate in 2013.
Members of the laboratory overseen by Professor Anton Bennett wrote in a statement to Yale University that Le was always up for a challenge and truly excited about her future as a researcher.
"Annie was a caring individual who would selflessly put the needs of others before her own," the members of the lab wrote. "She would never say 'I can't', but always, 'How can I help?'"
Le's accused killer has been repeatedly described as a man who seemed to have two very different personalities -- that of an outgoing and competitive all-American boy and that of a control freak who would allegedly abuse his girlfriends.
Clark is next due in court Oct. 6.
ABC News Correspondent Lisa Fletcher and The Associated Press contributed to this report.