Michael Welner, a top forensic psychiatrist and an ABC News consultant, said today on "GMA" that if Skelton is involved in the disappearance, he may have been feeling a "heightened sense of failure."
"Pride is very much tied into financial ruin and there are some fathers in states of deep depression, sometimes accelerated by alcohol or other substance abuse, who might feel that they can't face their children seeing them fail," said Welner.
"They may feel that they're doing the children a service, that they won't be homeless, improverished and have a father in ruins," he said.
Skelton has not been named a suspect in his childrens' disappearance but authorities are asking for the public's help in locating his car which Weeks said was not at the home Thursday and Friday. Specifically, Weeks wants to know whether anyone saw the car between 2:30 p.m. Thursday and 1 p.m. Friday.
"Authorities have information that the vehicle was not at home during some of that time and believe the boys were in the car that morning or the evening before," Weeks said.
The blue 2000 Dodge Caravan, license plate No. 9JQ H93, has since been towed from Skelton's home, according to the Detroit Free Press.
Investigators are also expanding their search to the Ohio-Michigan border, specifically in Holiday City in Ohio, and said they have taken several items from Skelton's home. Weeks declined to comment on whether authorities had seized Skelton's computer.
Doug Rowland, the owner of the Lazy River Campground in Pioneer, Ohio, told ABCNews.com that about 60 investigators visited his property today to search for the boys but came up empty handed.
Rowland said police told him they were working on a lead from a "ping" they got off a cell phone and they also suggested that Skelton himself mentioned a campground during an interview.
Police have said that the boys, who have been missing for four days, could be in "extreme danger."
"We remain hopeful," Weeks said. "That's why we're doing what we're doing to find these boys and bring them home."
The grandmother of the missing boys earlier today made an emotional plea for their return.
"We just have to reach out to this person and relay how very important it is that they come home to their mom," said Roxann Skelton, the boys' fraternal grandmother. "[Taylor] needs to put herself in the mother's position for five seconds and multiple it by one thousand and she'd realize the pain and hurt and terribly agony the family is going through for these boys."
Search crews, as well as hundreds of volunteers, looked for the boys throughout the weekend, focusing much of their efforts in wooded areas surrounding Skelton's home.
Asked how she knows her son is telling the truth about Taylor, Roxann Skelton responded, "Because I know my son. ... He loves his boys, his boys are his life, it's as simple as that.
"Whether her name is Joann Taylor or Mary Poppins doesn't matter to me, all I know is that these children are with her, I know this," she said. "Those boys are out there terrified, but they are out there.
"Those children need to come home to their mother and if she can't bring them home, if she feels for some reason she can't do it, drop them off to a house of safety; a fire department, a police department, a McDonald's, for heaven sake," she said. "Anything, just bring these boys home with their mother where they belong."