Press secretary Sarah Sanders leaving White House

"She is a very special person with extraordinary talents," Trump tweeted.

At an event aimed at highlighting hiring efforts for former inmates, Trump praised Sanders calling her "a warrior."

"We've been through a lot together. She's tough, but she's good," he said and added, "If we can get her to run for the governor of Arkansas, I think she'll do very well."

Sources familiar say Sanders has not revealed whether she might consider mounting a political bid of her own back in Arkansas, but a person familiar said there has been speculation among staffers in the White House about the possibility of Sanders pursuing a political career.

Sanders described her role as "the honor of a lifetime."

"This has been the honor of a lifetime, the opportunity of a lifetime… particularly to work for this president," she said adding it is "something I will treasure forever .. loved every minute…even the hard minutes."

Sanders gathered members of her staff Thursday afternoon and informed them of her planned departure at that time. Sources familiar with Sanders decision to depart cited her desire to make the move back to Arkansas for the sake of her family. Sanders and her husband have three young children, all under the age of ten, and sources said she and her husband felt now was the right time to move the family and get them settled back in Arkansas during the summer school recess.

Sanders was named White House press secretary in July 2017, just hours after Sean Spicer resigned from the position. Over the course of her tenure, the traditional daily White House press briefings ceased to occur on any regular basis. Sanders last briefing was more than three months ago, 94 days before the date of her announced departure.

While Sanders formally briefed far less than a traditional press secretary, she became one of the president's closest and most trusted advisers in the West Wing and has been by his side for three and a half years, first during the campaign and then in the administration. She is one of the few White House aides who traveled with the president on every single foreign trip he has made – attending his meeting with Kim Jong Un and sitting next to Prince Charles at dinner with the president just last week in London.

Sanders came under criticism for her May 2017 claims that "countless" FBI members had told the White House they had "lost confidence in" former FBI Director James Comey, a comment that she later said was a "slip of the tongue" and "not based on anything" during an interview with Special Counsel Robert Mueller's team of investigators but then later sought to defend.

When presented with the discrepancy documented in Mueller's report, Sanders refused to acknowledge that she had made a deliberate, false statement to the American people.

"Actually, if you look at what I said, I said the 'slip of the tongue' was in using the word 'countless,'" Sanders contended in an interview with George Stephanopoulos in April, "but there were a number of FBI, both former and current, that agreed with the president's decision, and they've continued to speak out and say that and send notice to the White House of that agreement with the president's decision."

Sanders is the daughter of former Arkansas governor and two-time presidential candidate Mike Huckabee and grew up with a fascination for politics.

“I always say that when most kids are seven or eight years old out jumping rope, she was sitting at the kitchen table listening to [political commentators] analyze poll results,” her father told Fox News in May of 2017.

Sanders confirmed earlier this year that she has been interviewed by special counsel Robert Mueller's team investigating Russian interference in the 2016 presidential election.

“The President urged me, like he has everyone in the administration, to fully cooperate with the special counsel. I was happy to voluntarily sit down with them,” Sanders said in a statement to ABC after the news was first reported by CNN.

One source told ABC News the interview happened around the same time that it's believed other White House officials were being brought in for interviews.