A U.S. citizen has been arrested crossing back into the U.S. from Mexico after authorities found an estimated $130,000 of fentanyl hidden in the taxi they were riding in.

Publicis Groupe SA agreed Thursday to pay $350 million to settle claims it helped OxyContin maker Purdue Pharma fuel the opioids epidemic in the United States.

Oregon officials declared a 90-day state of emergency to address Portland’s fentanyl crisis as fatal synthetic opioid overdoses there have risen 533% since 2018.

A pharmaceutical company says their new experimental drug could be an alternative to opioid-based painkillers.

Advocates feel presidential candidates have not discussed substance use disorder much – when, they believe, it should be highlighted both during and beyond the primary.

Grammy-nominated musician Jelly Roll delivered an impassioned testimony before senate as lawmakers push for new anti-fentanyl legislation.

Republican presidential candidate and former New Jersey Gov. Chris Christie outlined his national drug crisis plan earlier this week.

Several Virginia elementary school students needed medical attention Tuesday after eating gummy bears from a bag that tested positive for fentanyl, authorities said.

A settlement with Purdue Pharma hung in the balance at the Supreme Court as victims of the opioid epidemic urged justices to approve a deal with the company's owners.

As tens of thousands of Americans die each year from synthetic opioids, namely fentanyl, federal officials say the illicit narcotics trade remains a critical problem

New details of a federal investigation into a "massive" fentanyl ring in D.C. and elsewhere were released Monday with 11 additional arrests -- out of 23 total

Senior government officials are concerned that Congress may not pass enough funding to secure the border, as federal authorities work to stop illegal narcotics smuggling.

Two of the three suspects arrested in the death of a 1-year-old boy from fentanyl exposure at a Bronx, New York, day care center pleaded not guilty Thursday.

The machine-printed banners were purportedly signed by a faction of the Sinaloa cartel led by the sons of jailed Mexican drug lord Joaquin "El Chapo" Guzman.

Felix Herrera Garcia, the husband of the owner of the Bronx day care where a 1-year-old died of suspected fentanyl poisoning, returned Thursday to the United States.

The overdose crisis reaches historic levels in New York City, according to new data from the city's Department of Health and Mental Hygiene.

Two people in custody over the death of a 1-year old boy at a New York City day care are facing federal charges.

DHS looks to combat illicit drugs inside and out of the United States through targeted strategy

A 1-year-old boy has died and three other children were hospitalized after apparently coming into contact with an opioid at a day care center, according to the NYPD.

Illegal drugs are expected to be one of the biggest threats to national security in 2024, according to the Department of Homeland Security's annual threat study.

The percentage of overdose deaths from fentanyl combined with stimulants increased 50-fold between 2010 and 2021, according to a new analysis done by researchers.

The manufacturer of the overdose reversal drug Narcan said it will be available to buy over-the-counter starting in September.

The Supreme Court on Thursday temporarily blocked Purdue Pharma’s plan to emerge from bankruptcy that shielded the Sackler families from liability in the opioid epidemic

Xylazine, known on the street as tranq, is a cheap and powerful sedative, often used as a horse tranquilizer and is at the center of overdose deaths.

The California Highway Patrol has seized enough fentanyl in San Francisco in the past six weeks to kill the city's entire population nearly three times over.

Doctors who run ketamine clinics say that cash-only ketamine clinics face unique economic challenges.

A 17-year-old girl has been charged with murder in the overdose deaths of two of her classmates. The deceased teens were 16 years old and 17 years old.

School districts nationwide are scrambling to acquire Naloxone, train people how to use it, and combat stigma from openly acknowledging problems with addiction.

Approximately 300,000 fentanyl pills and more than 11 pounds of powdered fentanyl were recently recovered from the gas tank of an SUV in the Bronx, prosecutors said.

DOJ and FBI hold a presser at DOJ announcing the results of “the largest international operation” targeting fentanyl and opioid trafficking on the Darknet.

A nonprofit is tackling fentanyl overdoses by passing out test strips and Narcan and educating people on what to do if they suspect someone is having an overdose.

The head of a police union in the Bay Area faces federal charges for allegedly smuggling thousands of synthetic opioids into the U.S. with the intent to distribute them.

The FDA approved the overdose reversal drug Narcan for over-the-counter use Wednesday.

DEA issues public safety alert for mixture of powerful veterinary drug with fentanyl

New data from the North Carolina Department of Health and Human Services shows more than 4,000 people -- a record high -- died from drug overdoses in 2021.

Families are suing the company behind Snapchat, alleging the social media giant enables drug dealers to sell lethal drugs to children online.

The Canadian province of British Columbia said it's decriminalizing small amounts of some drugs to help combat the number of drug overdose deaths.

Freeda Flynn was found guilty on eight counts of unlawfully distributing controlled substances, including oxycodone, hydrocodone and methadone

A man was sentenced to 20 years in prison for the death of a 19-year-old who bought what appeared to be prescription oxycodone pills that actually contained fentanyl.

New York seized 1.9 million fentanyl-laced, fake prescription pills in 2022.