Oprah Winfrey has confirmed she is on a weight loss medication and says she no longer believes her weight struggles are her fault.

Winfrey revealed in December that she takes a prescription drug for weight loss.

Shares in WeightWatchers dropped by 25% after Oprah Winfrey announced that she has decided not to stand for re-election at the annual meeting of shareholders in May.

Oprah Winfrey celebrated Quinta Brunson's historic Emmys win by sending a massive bouquet of flowers to the "Abbott Elementary" set.

Winfrey spoke about the years of shame she says she experienced for her weight.

Oprah Winfrey and Dwayne Johnson have teamed up to establish the People's Fund of Maui to help those affected by the recent wildfires.

Oprah Winfrey shared a tribute to her late father, Vernon Winfrey, who died July 8 at the age of 88.

Winfrey confirmed earlier this year that the magazine's December 2020 issue would be its last monthly print edition.

The donation will assist organizations in places close to her heart: her hometown of Kosciusko, Mississippi, Chicago, Nashville, Milwaukee and Baltimore.

Oprah Winfrey's commencement speech to the class of 2020: "To be the class that commenced a new way forward," she said, "bravo."

The former talk show host will curate the four-week program. "Together, let’s reset, refocus, and find clarity in what matters most," she said.

And yes, one of them was the book Meghan read to him in his birthday video.

Facebook and Instagram are throwing a virtual graduation for the class of 2020, including a commencement address from Oprah Winfrey and a performance by Miley Cyrus.

For Oprah’s "2020 Vision: Your Life in Focus" tour, the grand dame of self-love has recruited some famous friends to join her and spread the good word.

One Morehouse student now has a brand new iPhone -- thanks to Oprah Winfrey.

"If we had married, we would not be together,'” she said of her partner.

Oprah Winfrey is continuing to give back to HBCUs in a major way.

Oprah Winfrey recently said she "would love to" do a talk show again, just not everyday.

"I'm dedicated to her happiness," Graham revealed.

Brie Larson is a renown actress with millions of fans across the globe, but even she still gets a little starstruck sometimes.

The 10th Annual Women in the World Summit began Wednesday night and what better self-made icon to kick things off than Oprah Winfrey.

She went home twice to make sure she said all she needed to before her death.

The media mogul spoke out late Monday after news of her mother's death.

She died on Thanksgiving and has already been laid to rest.

President Trump and former President Obama also will campaign in Georgia.

"I would not be able to do it. It's not a clean business," she told Vogue U.K.

It turns out Winfrey is a major fangirl of Hulu's Emmy Award-winning series.

"The Sun Does Shine" details life on death row.

"Your legacy is every life you touch," she told the graduates. Also? "Recycle."

The young actress discussed with "GMA" the incredible experience of working with some of the best female talents in Hollywood and how it has changed her life.

"A Wrinkle in Time" star Reese Witherspoon dishes on her new projects.

Oprah went from playing with corn cob dolls to being made into a Barbie doll.

Winfrey is starring in the female-driven "A Wrinkle in Time."

She conducted a pair of controversial roundtable discussions that Trump slammed.

Oprah Winfrey has responded to President Donald Trump's tweet from last week calling a "60 Minutes" segment she did "biased and slanted."

"It’s not something that interests me," she said.

Winfrey gave Recy Taylor a nod in her Golden Globes speech.

Former Obama Campaign Manager thinks it’s all about the economy.

Earlier in the day, long-time friend Gayle King pushed back on the speculation.

Few Americans are as well-known and well-loved as the long-time media mogul.