"Once she brings Obama on and opens the door to political people [on her show], it's only fair to bring both Republicans and Democrats on," she added.
But, according to mother and Winfrey fan Donna Chaffins, when Obama appeared on the show does matter.
"Personally, as long as she claims she will not use her show as a platform and as long as she doesn't campaign for him on the show, I have no problem with her waiting to have Palin on the show," Chaffins said.
Chaffins said that she "would have an issue" if, now that nominations have been decided, Winfrey had only the Democratic candidates on and not the Republicans.
"I want her to be fair," said Chaffins, who is undecided on whom she will vote for come November.
While Winfrey's endorsement of Obama is here to stay, why she will not invite Palin on her show, as one of the powerful women she often features, is unclear to many fans who said that regardless of her policies, Palin is making history.
"Whether you agree with Sarah Palin and her positions or not, the fact that she's the first female Republican vice presidential candidate is historical," said Joanne Bamberger, who runs the blog Punditmom1.blogspot.com.
"I'd have to imagine her audience would really want to see Palin," said Bamberger, who said that she is voting Democratic but still would love to see Palin interviewed by Winfrey. "It seems to me that Winfrey's show is all about empowering women."
By not having Palin on the show, Grossman-Green says that Winfrey is actually doing a disservice to her predominantly female audience, many of whom look for inspiration in the guests who appear on the show.
"She's doing an injustice to women by not having Palin on," Grossman-Green said. "Palin is a wonderful role model of what we're all trying to do as working women -- which is everything."
But not everyone thinks that it would make sense for Oprah to counter her support for Obama by allowing Palin to appear on her show.
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