Though officials will not confirm whether Rihanna is the accuser in the domestic abuse case, members of the hip-hop world and Hollywood are rallying around her and Brown.
"I was completely devastated by the concept of what I heard," Kanye West said Tuesday on Ryan Seacrest's KIIS-FM radio show. "Rihanna is so important to our culture ... to pop music. ... Her taste level and her age. ... She has the potential to be the greatest artist of all time."
"In that sense, I feel like that's my baby sis," West said. "I would do any and everything to help her in any situation."
According to Us Weekly magazine, rap mogul Jay-Z, who discovered and mentored Rihanna, "hit the roof" when he found out about the alleged fight.
Actor Terrence Howard came to Brown's defense Tuesday, telling Hollywood.tv, "Chris is a great guy. He'll be all right. And Rihanna knows he loves her."
But Wednesday, he released a statement saying, "When they asked me about Chris Brown the other day, I was in no way aware of what he had been accused of. Had I known, I would have never had said something so insensitive."
Rapper T.I., who is set to begin a yearlong jail sentence next month on federal weapons charges, told "Last Call's" Carson Daly that he spoke with Brown Feb. 9 and that the singer's "cool."
"He cool, you know. I guess he a little concerned about the situation, but he's still the same Chris," T.I. said. "I told him this too shall pass."
Brown's alleged violent behavior may be rooted in his past. In 2007, he told Giant magazine about how he grew up terrified, watching his stepfather abuse his mother.
"He used to hit my mom," Brown told the magazine. "He made me terrified all the time, terrified like I had to pee on myself. I remember one night he made her nose bleed. I was crying and thinking, 'I'm just gonna go crazy on him one day.' ... I hate him to this day."
Brown also told Giant he studied martial arts to defend himself. After a fight with classmates in which he broke out his moves, he begged his mother not to go to the police.
"Don't go to no cops pressing no charges," he told her, according to Giant. "Like, we don't do that in the 'hood."
"Chris Brown is like the all-American guy," Giant editor in chief Emil Wilbekin told ABCNews.com. "He's hardworking and a great talent. He may just be reacting based on what he knows, but it's scary and surprising."
For Brown, the backlash has come fast. Advertisers and radio stations have already backed away from the R&B singer. His "Got Milk" ad campaign ended last week.
"The Milk Mustache campaign is taking the allegations against Chris Brown very seriously," The Milk Processor Education Program said in a statement. "We are very proud and protective of the image of the Milk Mustache campaign and the responsible message it sends to teens. Mr. Brown's ad was launched last fall and is scheduled to end this week."
And Wrigley announced Feb. 9 that it would suspend its ad campaign featuring Brown as the spokesman for Doublemint gum.
"Wrigley is concerned by the serious allegations made against Chris Brown," the company said in a statement. "We believe Mr. Brown should be afforded the same due process as any citizen. However, we have made the decision to suspend the current advertising featuring Brown and any related marketing communications until the matter is resolved."