Before parting ways with her most recent film gig two weeks ago, Murphy struggled to keep her job on the film before that, "Something Wicked," which has not yet been released.
A production insider told TheWrap.com that Murphy "was barely there," and would "go in and out of consciousness in the middle of takes." The insider said folks on the set widely assumed Murphy was using prescription drugs.
The Los Angeles Times reported Monday that Murphy was taking prescription drugs for a variety of medical ailments, while TMZ said prescription drugs were found throughout the home Murphy shared with Monjack.
Winter confirmed that several legal prescription medications -- all made out to Murphy -- were recovered from her apartment and taken in as evidence. According to the coroner documents obtained by TMZ, Murphy's medications included Topamax (anti-seizure meds also to prevent migraines), Methylprednisolone (anti-inflammatory), Fluoxetine (depression med), Klonopin (anxiety med), Carbamazepine (treats Diabetic symptoms and is also a bipolar med), Ativan (anxiety med), Vicoprofen (pain reliever), Propranolol (hypertension, used to prevent heart attacks), Biaxin (antibiotic), Hydrocodone (pain med) and miscellaneous vitamins.
"No foul play is suspected," the coroner told ABCNews.com, adding that the cause of death "appears to be natural."
LuAnn White of the Tulane Center for Applied Environmental Public Health in New Orleans told ABCNews.com that it is uncommon for a seemingly healthy 32-year-old to suddenly die from cardiac arrest. White said she would look for congenital heart defects, prescription or illegal drug overdose or an eating disorder.
"Restrictive food or liquid intake and/or chronic vomiting associated with anorexia and bulimia can result in excessive loss of water and essential salts," which can lead to cardiac arrest, White said.
Murphy's death has also shined the spotlight on her husband once again. After a brief relationship with Kutcher and engagements to talent manager Jeff Kwatinetz and crewman Joe Macaluso, Murphy married the British screenwriter after just four months of dating.
Tabloid reports quickly surfaced that Monjack was a shady businessman facing major debts and deportation for an expired work visa -- something both Monjack and Murphy denied as "preposterous lies" to "In Touch Weekly."
"When she married him, people said, 'Who is this guy? What's going on?'" Malkin said. "He apparently had some money problems. He was evicted from three apartments, owed a mortgage company some money, which he paid back, was causing problems with her on the set of her movie. Whenever you hear about him, it was always for something shady."
Monjack has been the defendant in several lawsuits, according to documents obtained by ABCNews.com. In 2006, a British bank received a court judgment against him for $470,132. In 2005, before he met Murphy, Monjack and his girlfriend were evicted from their New York apartment for owing $7,025 in back rent.
His ex-wife Simone Bienne also took him to court in November 2007, six months after his marriage to Murphy, for $50,000 she claims she was never paid after their 2006 divorce.