Bono revealed to his parents that he was a lesbian at age 18 and wrote about the experience in his 1998 memoir, "Family Outing."
In 2002, Bono wrote "The End of Innocence," a second memoir about coming out, his music career, and his partner's death from non-Hodgkin's lymphoma.
According to Bono's books, Cher was shocked by the news of his sexuality and even banished Bono from her NYC apartment immediately after he came out.
"I'd always had this idea that she would get married and have a family," Cher told People magazine in 1998.
The two since have mended their relationship, though Cher reportedly expressed concern about Bono's weight. Bono participated in VH1's "Celebrity Fit Club 3" in 2003 in an effort to shed pounds.
Cher spoke out about Chastity's decision to change her gender from female to male in June, saying in a statement to Us Weekly magazine that "Chaz is embarking on a difficult journey, but one that I will support. I respect the courage it takes to go through this transition in the glare of public scrutiny, and although I may not understand, I will strive to be understanding. The one thing that will never change is my abiding love for my child."