The "$2.5 million off the top of money that we raise from the Viva Mac lipstick is going to go right to women right away," Lady Gaga said.
The lipstick and gloss come in eight shades and are sold for $14. MAC said that every cent of the selling price will go to the MAC AIDS Fund.
"I'm hoping and Cyndi's hoping that mothers and sisters and best friends buy each other this lipstick and say, 'This lipstick represents you protecting yourself, having safe sex and remembering to have loving, monogamous relationships to protect you and those around you,'" Lady Gaga said.
The highest new rates of infection are in women between the ages of 17 and 24, and between 39 and 60, Lauper said.
"It is like Boy Scouts; their motto is my motto. Be prepared. Always be prepared. …. You know the heat of the moment, I understand that, but it's not worth your life" Lauper said.
Lady Gaga said one reason she is supporting this campaign is because not enough women are educated about HIV and AIDS, and how quickly it is spreading.
"Everyone has that phone call: 'Oh my gosh, you wouldn't believe what I did last night,' and 'I was so stupid I didn't use a condom,' and there is all this laughter on the phone, because I have gotten those phone calls," Lady Gaga said. "And it is our jobs as friends to one another to say, 'I don't know why you are laughing because it is very serious.'"
Only five years out of high school, Lady Gaga has skyrocketed to fame. In addiiton to hits such as "Poker Face" or "Just Dance," her performances and taste in fashion have always been memorable.
"I've worked so hard, but being here today is sort of a whirlwind," Lady Gaga, who wore a hat made out of safety pins, said on "GMA." "I'm sitting next to a woman that I've admired my entire life, who is completely legendary as a fashion icon and as an artist that really really changed music for women. And I am speaking to you about a cause that affects women all over the world, and I never knew that I would be allowed to have the responsibility I have today."
Lauper, who refered to Lady Gaga as a 'kid,' had some advice for the young star.
"It is your time, it's time to be really creative. Don't listen if someone says, 'No, you can't do that,'" Lauper said. "There is no 'You can't,' and in the end, it all evens out. But you know if you get an idea, do it, or you'll forget about it and it will be frustrating. Just do it."