"It is like a death, you know. And in many ways it's like having part of your life amputated, but you still have that phantom itch, you know, where you wake up and I'll see something and think, 'Oh, I've got to make sure Lance is hip to this band. I've got to put it on his iPod.' And then I remember, 'Oh, wait, you know, that's not my life.'"
Crow keeps memories of the relationship close -- she made two albums that were deeply influenced by her time with Armstrong. She did not, however, keep her engagement ring from him.
"Oh Lord, no, I didn't," she said. "It was beautiful and a symbol of something really, really sweet. But at that moment, it was -- also represented a lot of pain, you know, and also was quite expensive."
"And I don't know what the etiquette is with something like that," she added with a laugh.
Today Crow has few regrets. She is ready to sing again, and continue learning the lessons that life teaches each of us every day.
"I wrote a song a few years ago called 'Every Day Is a Winding Road,'" she said.
"People go through challenging moments of losing people and of having their life threatened from illness and real grief. But they get through it. And that's the testament to the human spirit and it's -- we're fragile, but we also are divine."
Watch Part 2 of the exclusive interview with Sheryl Crow Friday on "Good Morning America."