Officials Investigate Infants' Heparin OD at Texas Hospital

July 10, 2008 — -- Texas authorities are investigating the death of two infants after a Corpus Christi hospital gave 17 babies in its neonatal unit an overdose of the blood-thinning drug heparin.

Christus Spohn Hospital South said it has yet to determine if the deaths of the children, who were twins, are related to a heparin overdose that left another infant in critical condition. Twelve other babies remain in stable condition after receiving a dose that may have been 100 times too strong, while two more babies have been released from the hospital.

Two pharmacy staff members voluntarily took leave pending an investigation, and the 17-year-old parents of the two children who died have hired an attorney.

"They're in shock," attorney Bob Patterson said. "This is probably the worst thing that can happen to parents, as you might expect."

Hospital nurses discovered the error Sunday after receiving abnormal test results, according to HealthDay news service. The pediatric version of heparin was used to flush IV tubes to prevent blood clots from forming.

The exact amount administered to the infants remains unclear, but it is believed the error occurred in the hospital's pharmacy as the drug was being mixed, according to The Associated Press.

This isn't the first time a heparin overdose has made the headlines. Actor Dennis Quaid's 12-day-old twins, Thomas and Zoe, survived an adult dose of heparin last year that was 1,000 times too strong.

Quaid eventually went to Capitol Hill to talk about his family's ordeal and to stump for clearer distinctions between heparin labels.

"The 10,000-unit label, which I believe you have there, is dark blue and the 10-unit bottle is light blue; they are virtually the same," he told members of Congress.

Since then, drugmaker Baxter International has increased the size of the label by 20 percent and added red warning signs to adult doses.

"Labeling is just one piece of the puzzle in a lot of these errors that we see," said Allen Vaida, executive vice president of the Institute for Safe Medication Practices. "So although the new labeling is available and is out there, there's other things that have been going on. In fact, in the last six months, there's been a national recall of heparin because there was a contaminant that actually was coming out of China for the product."