"I love my sister, more than like [her]," Ciccone said. "I love her. It will take some time for us to find our way back to, to a good place, and I'm not sure when and if that will happen. I hope it does."
Ultimately, Ciccone insisted his explosive book was not an attempt to get revenge on his uber famous pop star sibling, who is currently busy battling allegations of a home-wrecking affair with New York Yankees third baseman Alex Rodriguez.
"I didn't set about to knock her off her pedestal. I set about to put [up] a nice little staircase up and help her walk back down to earth with the rest of us," he said.
"I'm not taking revenge at all," he added. "I'm telling what I consider to be a great tale."
Representatives for Madonna and Ritchie declined to comment on Ciccone's book and allegations.
For Ciccone, part of making his sister more humble is dispelling the myths surrounding her childhood and early career.
As a pop culture mainstay for more than 25 years, Madonna might already seem like an open book to her fans. The story includes her humble beginnings and her heading to New York City as a young woman determined to "make it big" with only $35 in her pocket.
But Ciccone said that's not the true picture of Madonna; those are just well-spun fairy tales. In fact, the queen of reinvention grew up in a middle class home as the third of six children, where she often got what she wanted.
Ciccone said he was by Madonna's side long before she was a Material Girl, tabloid staple or Kabbalah (Jewish mystical teachings) enthusiast. Two years her junior, he knew her as Madonna Louise Ciccone, an incredibly strong-willed, determined child.
She always did everything first — everything best, he said. And after their mother's death, more focus was placed on Madonna.
"Well, she was my mother's namesake, and she looked like my mother," Ciccone said. "Our mother was very important to us and she, you know, after dying, she, achieved a sort of sainthood in our family.
"And so, Madonna became the focus of quite a bit of attention. And it's — that attention turned into kind of an ego ... that got bigger and bigger."
Even as Madonna became pop music's new starlet, its bad girl, and its resident rebel, Ciccone said she still retained some of her roots.
"First of all, despite everything else, she's still a Catholic girl," he said.
Now, Ciccone believes that the Madonna of today doesn't resemble the girl he grew up with — either personally or physically.
"Not after the face-lift," Ciccone said with a chuckle.
"Frankly, I don't want to talk to her unless we're speaking to where — to each other as equals," he said. "That's where it has to come from. And if that means, you know, if that, if she stays together with her husband, and that means we don't have a relationship, as long as she's happy, it's cool with me."
Ciccone characterized Ritchie as a homophobe who destroyed his close relationship with his sister.
"Guy Ritchie pretty much happened to our relationship, for the most part," Ciccone said.