Does Long-Term Antidepressant Use Cause Any Known Problems?

Question: Does long-term antidepressant use cause any known problems?

Answer: Long-term antidepressant use does not cause any long-term problems. Sometimes, unfortunately, the antidepressant medications will stop working and are no longer effective or as effective as they had been earlier for the treatment of the depression.

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But it's highly unlikely that any new side effects will occur later on in treatment. Now, it is certainly possible that somebody may have a side effect from an antidepressant when they first get started that doesn't go away, but it's not as if a new side effect is going to start later on in the treatment when somebody didn't have it in the beginning.

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