A Woman's Brain Hit Harder by Alcohol Abuse

ByABC News
March 23, 2008, 11:41 PM

Mar. 23 -- FRIDAY, April 27 (HealthDay News) -- Alcohol abuse chips away at intelligence more in women than in men, even when less alcohol is consumed over fewer years, new research suggests.

Alcohol-related cognition problems affect drinkers' "visual working memory, spatial planning, problem solving and cognitive flexibility," said study corresponding author Barbara Flannery, a senior scientist at the research institute RTI International in Baltimore.

But it's not only drinkers' professional lives that may flounder as a result of reduced cognition, Flannery said. Alcoholics may have difficulty behaving appropriately in social situations, she said.

"Cognitive flexibility enables you to know how to communicate differently in a business environment than you would with your friends," she added.

The study findings were based on a comparison of test results from male and female alcoholics and non-alcoholics from Russia. All alcoholic participants in the study were recruited at the Leningrad Regional Center of Addictions.

The tests revealed that non-alcoholics trumped the alcoholics, who had been abstinent for three weeks, in a series of computerized tasks. The tasks evaluated the ability to match patterns in shapes, remember the locations of stimuli, and name colors when confronted with contradictory information.

The female alcoholics fared significantly worse in most instances than the male alcoholics, a finding that prompted Flannery to call for a "gender-sensitive public awareness campaign that highlights these cognitive deficits."

On average, the female alcoholics in the study had used alcohol for 10.6 years, compared to 14.8 years for the males.

The study corroborated previous research that found female alcoholics scored lower than their male counterparts in tests that assessed working memory, visuospatial skills and psychomotor speed. Other studies have shown that female drinkers experience accelerated damage to the liver, heart and muscles, compared with male alcoholics, the researchers said.