Discharged Hospital Patients Run Risk of Blood Clots

"Although these agents reduce thrombotic events, they do not reduce all-cause mortality, perhaps because many events are not life-threatening or because of other mortality risks or because adverse events of these agents offset their benefits," said lead researcher Dr. Henry Krum, a professor of epidemiology at Monash University, in Melbourne, Australia.

Compared with a placebo, unfractionated heparin was linked to a 67 percent lower risk of venous thrombosis and a 36 percent lower risk of pulmonary embolism. Low-molecular-weight heparin was associated with a 44 percent lower risk of deep vein thrombosis and 63 percent lower risk of pulmonary embolism, the researchers found.

When compared with each other, low-molecular-weight heparin was associated with a 32 percent reduced risk of deep vein thrombosis and a 53 percent lower rate of hematoma at the injection site. Fondaparinux sodium also prevented venous thromboembolism. But, using these drugs wasn't associated with lower death rates, according to the study results.

"These medications should be given to reduce thrombotic events, but do not expect to reduce mortality," Krum said.

Goldhaber believes that patients need to take an active role in making sure they are receiving treatment to prevent blood clots. "Patients should demand, during hospitalization, to know what is being done to prevent thromboembolism during this period of risk," he said.

More information

For more information on deep vein thrombosis, visit the U.S. National Heart, Lung, and Blood Institute.

SOURCES: Henry Krum, M.B.B.S., Ph.D., professor of epidemiology, Monash University, Melbourne, Australia; Samuel Z. Goldhaber, M.D., Brigham and Women's Hospital, Boston; July 23, 2007, Archives of Internal Medicine

Page
  • 1
  • |
  • 2
Join the Discussion
You are using an outdated version of Internet Explorer. Please click here to upgrade your browser in order to comment.
blog comments powered by Disqus
 
You Might Also Like...
See It, Share It
PHOTO:
St. Andre Bessette Catholic Church in Ecorse Michigan
A Gilchrist county sheriffs car sits at the end of a trailer home where 7 members of a family were slain by their grandfather in Bell, FL, Thursday, Sept., 18, 2014. The grandfather, Don Spirit, pictured, also killed himself.
Phil Sandlin/AP Photo | Gilchrist County Sheriffs Office
PHOTO: Kaley Cuoco Sweeting attends the 4th Annual Critics Choice Television Awards at The Beverly Hilton Hotel, June 19, 2014 in Beverly Hills, Calif.
Christopher Polk/Critics Choice Television Awards/Getty Images