University of North Carolina Hospitals, Chapel Hill, North Carolina

Hello. My name is Cam Patterson. I'm the chief of cardiology at UNC Chapel Hill and the director of the Carolina Cardiovascular Biological Center. We have a very broad research portfolio in cardiovascular diseases here at UNC that range from epidemiologic studies in collaboration with our school of public health to basic research studies going on in our cardiovascular research center to clinically-oriented studies going on here in the hospital.

One of the studies that I'm particularly excited about is the SMAR study. SMAR stands for supporting a multidisciplinary approach to research in atherosclerosis. And it's a study that combines gene expression profiling, genetics, proteomics, and metabolomics to help us find a better understanding of the causes and treatment of cardiovascular disease.

For example, we found in the SMAR study that smokers -- who are at an increased risk of cardiovascular disease -- have changes in proteins that are involved in how white blood cells divide. And we think that these circulating white blood cells may contribute to the increased risk of heart disease that we find in people who smoke.

In addition we found that in some African-Americans who had increased risks for heart disease, they have changes in proteins that are involved in breaking down sugars. And we think that these pathways may account for why some African-Americans are at a particular high risk for cardiovascular disease.

We think that through observations like these that we derive from the SMAR study that we'll be in the position to find new insights into the causes of cardiovascular disease and potentially also find better ways to treat cardiovascular disease -- the No. 1 cause of morbidity and mortality in our society.

-- This embed didnt make it to copy for story id = 4229567. -- This embed didnt make it to copy for story id = 4229567. -- This embed didnt make it to copy for story id = 4229567.
Join the Discussion
You are using an outdated version of Internet Explorer. Please click here to upgrade your browser in order to comment.
blog comments powered by Disqus
You Might Also Like...
See It, Share It
PHOTO: Makeup Artist Uses Chin as Canvas
Laura Jenkinson/Caters News Agency
PHOTO: Left, Texas Governor Rick Perry poses for his official portrait. Right, Perrys mug shot taken on August 19, 2014 after the Governor was indicted on two felony charges for an alleged abuse of power.
Texas State Governors Office | Travis County Sheriffs Office
PHOTO: Robin Williams and Billy Crystal walk the red carpet before a gala on August 4, 2012 in St. Paul, Minnesota.
Adam Bettcher/Getty Images for Starkey Hearing Foundation
PHOTO: Elise Mosca attends ABCs Bachelor In Paradise Premiere Party held at Mixology101 & Planet Dailies, Aug. 4, 2014, in Los Angeles.
Jesse Grant/Getty Images for Leisure Opport