Despite the mystery surrounding her legal views on Roe v. Wade, some abortion rights groups are cheering on her nomination.
"What more do women want?" National Organization for Women (NOW)'s President Kim Gandy said in a statement, citing Sotomayor's legal achievements. "We want a swift confirmation in the U.S. Senate."
Another hot button issue facing Sotomayor is same-sex marriage. Like abortion, Sotomayor's stance on the issue is unclear. But gay and lesbian groups hail her nomination.
Her "pattern of decision-making makes us more comfortable," D'Arcy Kemnitz, executive director of the National LGBT Bar Association, told ABCNews.com. "I believe that she is going to look at the matters that come before her with a fair mind. She is going to look at them with an empathetic point of view. She is going to ask the tough questions and be fearless in her determination."
With the California Supreme Court upholding Proposition 8, the controversial ballot initiative that banned same-sex marriage in the state of California, and talk that the case could escalate to the U.S. Supreme Court, same-sex marriage could become a hot topic in Washington in the near future.
Gay and lesbian groups hope Sotomayor's ruling will be on their side.
"We applaud President Obama for choosing Judge Sonia Sotomayor to become our nation's next U.S. Supreme Court justice," Joe Solmonese, president of the Human Rights Campaign, said in a statement. "We are confident that Judge Sotomayor has a demonstrated understanding and commitment to protecting the liberty and equality of all Americans."