"Women absolutely have it worse and Clinton is the most scrutinized because she's the most visible female candidate in the history of the United States," he said. "For me to be ugly is much easier. Clinton has to look matronly without looking beautiful, tough without looking harsh."
Ferraro, Democratic presidential candidate Walter Mondale's running mate in 1984, said her experience on the campaign trail was very different from Clinton's.
"I was only doing it for four months. These people have been doing it over a year," Ferraro said. "I had all the trappings of a national campaign, my own plane and I stayed in the best hotels and had Secret Service — it's very different."
"You really have to have the drive and the energy and the desire to do something like this," added Ferraro, who has endorsed Clinton.
American University's Brewer said she hopes voters realize it's not a candidate's appearance, but rather their stance on issues that should matter most.
"This is not a beauty pageant and it becomes distracting when people begin to think all that matters is looks," Brewer said. "An unflattering photograph of Clinton or any other female candidate does not qualify her for being credible and willing to serve."
"I don't know if we can avoid [discussing it], but it would be better if everyone was taken on their merit — everything else is just a distraction," she said.