McCain made the remarks today after receiving the endorsement of evangelical leader John Hagee, founder and senior pastor of the 19,000-member Cornerstone Church in San Antonio.
Hagee cited McCain's support of Israel and his opposition to legal abortion as reasons why he was backing him.
The pastor is best known in some Washington circles as a founder of Christians United for Israel and for his belief, as laid out in his book "Jerusalem Countdown" that the end of days scenario as spelled out in the Book of Revelation will occur after Russia, allied with the Islamic world, attacks Israel.
"Russia is going to get in that position and they are literally, with all that massive military force, going to attack Israel," Hagee told ABC News in 2006. "This is recorded in Ezekiel 38 and 39. God himself is literally going to destroy that army. Decimate it."
Hagee added that the confrontation would be followed by a Chinese army of 200 million coming to the city of Armageddon, where they will meet British and U.S. forces in the Battle of Armageddon.
"At that point, Jesus Christ returns to Earth and sets up his eternal kingdom in the city of Jerusalem and there's 1000 years of peace," Hagee said. "The Jewish people are going to see the supernatural hand of God preserve them and deliver them while the enemies of Israel are crushed. That's the end-time story."
Asked if he subscribed to this theology, McCain furrowed his brow.
"All I can tell you is I'm proud to have Pastor Hagee's support," he said.
Hagee added that his "support of Israel has absolutely nothing to do with an end times prophetic scenario. Our support of Israel is because we feel their cause is just. ... I support Sen. McCain because I know that he has pledged to be a strong defender of Israel."