Supporters of decriminalizing marijuana are hoping to build momentum on Capitol Hill after a historic election that saw the politics of pot take center stage in four states.
But today, the National Cannabis Industry Association, launched in December to represent the interests of legal marijuana growers and distributors, will hold the first congressional lobbying day in the nation's capital, hoping to shore up support for an industry they say could bring billions of dollars in revenue to the government.
The industry already has some notable lawmakers on its side.
Rep. Barney Frank, D-Mass., has in the past introduced legislation to remove federal penalties for personal use of marijuana. Libertarian-leaning Rep. Ron Paul, R-Texas, is also an outspoken advocate of full marijuana legalization.
Last summer, Frank and 15 other lawmakers sent a letter to Treasury Secretary Tim Geithner asking his agency to set rules that provide financial services to medical marijuana dispensaries and to assure banks they won't be penalized for conducting such business.
Today's lobbying efforts will focus on eliminating such restrictions and on easing the tax burden on medical marijuana clinics.
Supporters of decriminalizing marijuana say it will help the United States in the long term by boosting profits for the government. Socially, they say it will boost resources to crack down on hard drugs and will curb teen marijuana use, which is on the rise.
"Regulation will absolutely succeed in keeping it out of the hands of kids more effectively than prohibition because prohibition has created a large underground market," Rep. Jared Polis, D-Colo., told ABC News. "If you legalize it just like we have with alcohol, you will have a much better control.
"It would really provide America with a leg up on the drug war by preventing the marijuana engine that fuels the coffers of the [Mexican drug] cartels," he said. "You have more resources to crack down on hard drugs."
Others also tout its economic benefits.
According to a recent report by an analyst firm See Change Strategy, the national market for medical marijuana is worth $1.7 billion in 2011 and could reach $8.9 billion in five years. The black market, the report stated, is estimated at $18 billion.
In California, cannabis is the biggest cash crop, worth $14 billion in sales, nearly double the state's second biggest revenue generator, dairy.
Forty-six percent of Americans support legalizing marijuana, a new high, according to a survey conducted by Gallup in October. The trend has shifted upward in recent decades while opposition to such a move has declined.
For medical marijuana use, the support is even higher. Seventy percent of Americans said they favored making marijuana for medicinal purposes legally available.