A Democrat in a red state that got redder after Hurricane Katrina depleted the population of New Orleans, Sen. Mary Landrieu is a top target for national Republicans. State Treasurer John Kennedy, a moderate who switched from the Democratic to the Republican Party in August, might oppose Landrieu, but he has not yet announced. A special election must be held for the House seat of Bobby Jindal, who last month was elected governor.
2004 results: President Bush won the state's nine electoral votes with 57% of the vote.
Republican Sen. Susan Collins could face a tough challenge from six-term Democratic Rep. Tom Allen. Allen, who voted against authorizing use of force in Iraq in 2002, has criticized Collins' support of the Iraq war. More than a half dozen Democrats and Republicans have lined up to compete for Allen's House seat.
2004 results: Sen. Kerry won the state's four electoral votes with 54% of the vote.
Rep. Wayne Gilchrest, one of only two congressional Republicans to vote this year for troops to begin coming home from Iraq in the fall, looks to face a serious primary challenge. State Sen. Andrew Harris, Joseph Arminio, co-founder of a Washington, D.C.-based defense advocacy group, and John Leo Walter, a lawyer in his first run for office, will oppose the 16-year incumbent. Harris, running to Gilchrest's right, has the support of former governor Bob Ehrlich.
2004 results: Sen. Kerry won the state's 10 electoral votes with 56% of the vote.
With no Republicans in statewide office or Congress, Massachusetts is clearly Democratic territory, but the state's presidential hopeful is former governor Mitt Romney, a Republican. Massachusetts has not voted for a GOP presidential candidate since Ronald Reagan.
Democratic Sen. John Kerry has challengers to the left and right in his re-election bid. Former Gloucester city councilor Edward O'Reilly will oppose Kerry in the primary, and Republican Jeff Beatty, who founded a security consulting firm, plans to run in the general election.
2004 results: Sen. Kerry won the state's 12 electoral votes with 62% of the vote.
Freshman Republican Rep. Tim Walberg could face a battle for a second term from either state Senate Minority Leader Mark Schauer or Sharon Renier, who opposed Walberg in 2006. Republican Rep. Joe Knollenberg could also face a stiff re-election challenge from Democrat Gary Peters. Peters, a former state lottery commissioner has the financial support of the Democratic Congressional Campaign Committee.
The state's decision to move its presidential primary to Jan. 15 violates Democratic National Committee rules, and the DNC could take away Michigan's delegates. Democratic presidential contenders Barack Obama, John Edwards, Bill Richardson and Joseph Biden have all taken their names off the Jan. 15 ballot, but front-runner Hillary Rodham Clinton has not, saying that could hurt her in the general election.
2004 results: Sen. Kerry won the state's 17 electoral votes with 51% of the vote.
The 20% margin of victory for Amy Klobuchar in her 2006 run for an open Senate seat has Democrats energized to challenge Sen. Norm Coleman. He narrowly won the seat in 2002, after incumbent Paul Wellstone died in a plane crash weeks before the election. Comedian Al Franken is among hopefuls for the Democratic nomination.