An aide to another potential Republican presidential candidate, Louisiana Gov. Bobby Jindal, played down the decision's relevance to his state.
"Does it include Louisiana?" asked Jindal spokeswoman Melissa Sellers.
Pam Pryor, a spokeswoman for Sarah Palin, told ABC News that the Alaska governor would not comment on the Iowa marriage ruling even though she is an ardent opponent of same-sex marriage.
Despite losing in court on Friday, social conservatives hope they will prevail by amending the state constitution.
"Same-sex 'marriage' continues to be a movement driven by a liberal judicial elite determined to destroy not only the institution of marriage, but democracy as well," said Tony Perkins, the president of the Washington-based Family Research Council. "The casual dismissal of the facts of human biology and thousands of years of human history, simply to pander to a small band of social radicals, is bizarre and indefensible."
While same-sex marriage opponents hope that Iowa will follow California in overturning a decision of its state Supreme Court, supporters of same-sex marriage are emboldened by the fact that it is considerably more difficult to amend the state constitution in Iowa than it is in California.
"The Iowa Constitution can't be changed quickly," said state Sen. Matt McCoy, Iowa's first openly gay state lawmaker, in a YouTube video released Friday.
A state constitutional ban on same-sex marriage would need to be approved by two consecutive legislative sessions, the 2009-10 session and the 2011-12 session, before going to the voters in a general election referendum, according to the Iowa secretary of state's office.
This means that the earliest Iowa voters could weigh in on this issue would be in November 2011: smack-dab in the middle of the Republican Party's 2012 nomination fight.