Kroenke, who resides in Columbia and has ties to the University of Missouri, offered his blessing, and Fisher dialed Sam's number.
"I am overwhelmed, I am excited and I'm proud to be a Ram," Sam said. "I knew I was going to get picked somewhere and every team that passed me I was thinking of how I am going to sack their quarterback."
With that type of talent around him it won't be easy for Sam to make the roster.
"It's going to be very competitive for him, as it will be for some of the other guys with later picks, because of the depth and the talent level at the position," Fisher said.
Fisher also made it clear that Sam will be judged solely on his performance on the field.
Sam's teammates echoed those sentiments.
"Obviously people are going to make something out of it," Long told ESPN.com. "He's not the first gay player to ever play football. He might be the first openly gay professional football player, but there's all types of people from all over in an NFL locker room, it really is a melting pot and it never ceases to amaze me how a locker room can just mesh, people from all different walks of life, so I don't think it's an issue. He's coming to a really good D-line room."
Collins said he also texted Sam in support.
"I sent him a text and hoped he would have gone to my team, the Indianapolis Colts," Collins said. "But I am very happy for Michael that he got drafted and that his dream is coming true and he will have an opportunity to make the team and I wish him luck."
Sam, who said Saturday, "I feel like I'm Clowney" given all the attention he has received since being drafted, saw his followers on Twitter grow by more than 20 percent to 115,500 within two hours of being picked.
However, not everyone was supportive.
Soon after Sam was drafted, second-year Miami Dolphins player Don Jones tweeted "OMG" and "horrible." Those tweets since have been deleted, and Dolphins general manager Dennis Hickey said he plans to "sit down with Don Jones and address [the comments] and handle it appropriately."
Former Texas starting quarterback Case McCoy, meanwhile, tweeted, "ESPN ... You serious right now?" after Sam embraced his boyfriend on national TV after receiving the call from the Rams.
Earlier this week, Sam signed his first endorsement deal, partnering with Visa. Although his marketability is likely to be tied heavily to making a team and playing well, he has received dozens of endorsement deal offers, which is unprecedented for a late-round pick.
Saturday night, an excitable Sam spoke loudly and pointedly about his draft experience, pointing out that he believes he should have been drafted higher after earning so many accolades in 2013.
According to Sam, that will only serve as further motivation.
"In all honesty, from last season alone, I should have been a high, first three rounds [pick]," Sam said. "SEC Defensive Player of the Year, unanimous All-American, I should have gone in the top three rounds easily. But you know what? It is what it is. I'm happy to be a St. Louis Ram. Everything else is history."
In more ways than one.
ESPNNewYork.com's Ohm Youngmisuk, ESPN.com Dolphins reporter James Walker and ESPN.com's Darren Rovell contributed to this report.