Coming Up: Secretary of State Hillary Clinton, Defense Secretary Robert Gates, Sen. Jon Kyl and Sen. Charles Schumer

— -- After a week when the President announced a new nuclear weapons policy, signed a new nuclear arms treaty with Russia, and prepared for a big summit in Washington next week "This Week" Anchor Jake Tapper sits down with Secretary of State Hillary Clinton and Defense Secretary Robert Gates.

How much has US nuclear policy really changed? Will it, as critics argue, reduce deterrence to rogue states? We'll also ask the President's two top foreign policy officials about the other issues dominating their agendas including the latest on the unrest in Kyrgystan and the Administration's relations with Afghanistan President Hamid Karzai.

Plus, with the announcement of Justice John Paul Stevens' retirement, the President's choice for a successor could reshape the Court - will the next Supreme Court Justice nominee be more liberal than Justice Stevens? Will Republicans make good on their threat to filibuster? Are we in for another bitter confirmation fight? Two key Judiciary Committee Senators join us exclusively to preview the battle on Capitol Hill, Sen. Jon Kyl (R-AZ) and Sen. Charles Schumer (D-NY). Only on "This Week."

Then our "This Week" roundtable: George Will, Arianna Huffington, Cokie Roberts and Sam Donaldson look at changes to U.S. nuclear policy, the Supreme Court vacancy, Afghanistan, Tiger Woods' return to golf and all the week's politics. You won't want to miss it.