We do begin with a thanksgiving journey that ended in horror today along a major stretch of highway in texas. Thick fog triggering a deadly pileup. Look at this video, taken by a couple that came upon... See More
We do begin with a thanksgiving journey that ended in horror today along a major stretch of highway in texas. Thick fog triggering a deadly pileup. Look at this video, taken by a couple that came upon the massive accident. You can see some of the fog there. As it cleared late today, you could see the extent of the damage. Cars smashed into one another and families who were on their way to thanksgiving dinner. A mother holding her child close, children in tears. We lead off tonight with the rising toll. Abc's ryan owens is in texas for us. Reporter: From the air, the crush of cars and trucks almost look like toys. From the ground, the reality is devastating. As many as 150 vehicles piled together. Two died in this mangled metal. Up to 100 others spent this holiday in the hospital. I literally was able to stop without hitting anyone but sat there with that panic of who might hit me. Oh, my god. Reporter: Fog blinded drivers on this stretch of texas highway. Investigators say most couldn't see a foot in front of them at 8:00 this morning. It happened on interstate 10, about 80 miles east of houston. I-10 runs from florida to california. Both sides were shut down for hours. Tens of thousands hoping to get to their thanksgiving meal were stranded. The cause of the accident was a heavy fog bankrolled into this area which caused no one being able to see and one accident triggered another in a chain reaction. Reporter: Fog-related collisions are among the deadliest. Earlier this year, 20 died on a florida highway, enveloped in a choking mix of fog and smoke from a brush fire. Today in texas, this 5-year-old boy suffered minor injuries when a semi slammed into his mother's suv. Its other precious cargo, the thanksgiving turkey. Little damian ortiz used it to make sandwiches for the other injured. A roadside meal for those truly thankful, just to be alive. Ryan owens, abc news, dallas.
This transcript has been automatically generated and may not be 100% accurate.