Oct. 24, 2013 -- intro: It looks like one of Hollywood's hottest women is single again.
According to multiple reports, Minka Kelly and Chris Evans have called it quits for the second time. Kelly and Evans, best known for his superhero roles, broke up for the first time in 2007, before reuniting in August 2012.
According to E! online, their busy schedules are to blame.
The 33-year-old actress is filming the TV series "Almost Human" in Vancouver, while Evans, 32, is about to direct his first film, "1:30 Train," in New York City.
According to Us Weekly, the duo are parting on friendly terms and "still care about each other."
Kelly's been known to give her boyfriends a second chance, but it remains to be seen if there will be a third.
Click through to see more of the "Friday Night Lights" star's past loves.
quicklist: 1title: Donald Faisontext: Before she dated Evans, Kelly was paired with "Scrubs" actor Donald Faison for about a year until 2005. Faison is now married to Jessica Simpson's BFF CaCee Cobb and they recently became parents to son Rocco. media: 20672126
quicklist: 2title: John Mayertext: After Kelly broke up with Evans the first time, she dated singer John Mayer off and on between 2007 and 2008. They officially broke it off in early 2008 and he quickly jumped into the arms of Jennifer Aniston. When asked about Mayer's rebound, Kelly told People, "I'm really happy – as long as they're happy, I am." media: 20671673
quicklist: 3title: Derek Jetertext: Kelly quickly moved on to Derek Jeter, 39, entering in a three-year relationship with the New York Yankees shortstop before they called it quits in August 2011. The couple gave their romance another shot in January 2012 before finally parting in March of that year.media: 20670922
quicklist: 4title: Wilmer Valderramatext: Before giving Evans a second shot, Kelly was linked to "That '70s Show" star, Wilmer Valderrama. The pair were spotted last spring cozying up in a couple of Hollywood nightclubs.media: 20672000