After all, it is the awards show that recognizes how artists visually showcase the music we've fallen in love with over the past year.
Artists speak out
With music lovers from around the world turning in, many singers took the opportunity to sound off on causes important to them. The late Michael Jackson's daughter, Paris, spoke out about white supremacy while presenting the first award of the night.
"We must show these Nazis...[that] as a nation with liberty as our slogan, we have zero tolerance for their violence, their hatred and their discrimination," she said onstage. "We must resist."
Jared Leto remembers Chester Bennington
His friend Jared Leto, who went on tour with him, said onstage that "Chester was my friend as he was to so many and witnessing his life taught me important things especially about working relentlessly, pursuing dreams and being kind and caring while doing it."
Bennington's band, Linkin Park, then performed a song in his honor.
Who had the best performances?
Amid the dozens of performers who took the stage inside the Forum in Inglewood, California, there were a few who stood above the rest.
Kendrick Lamar's opening performance of his hit songs, "DNA" and "Humble" was on fire -- literally. The rapper tapped a dancing man who was ablaze to dance alongside him while background dancers battled flames and performed acrobatics. The performance even brought comedian Ellen DeGeneres to her feet.
Demi Lovato also had a memorable performance. It wasn't on the main stage. Instead, the singer performed at the pool inside the Palms Hotel and Casino in Las Vegas. Lovato performed her hit song, "Sorry Not Sorry," as fans took to the water.
But one of the most moving performances was by Logic, Khalid and Alessia Cara. The three performed a song called, "1-800-273-8253," about suicide prevention. They were joined by suicide survivors onstage, who at times became tearful.
MTV addresses Charlottesville
The awards show also addressed the recent white nationalist rally in Charlottesville, Virginia, by inviting a descendant of Robert E. Lee, the Confederate general, to appear with Susan Bro, the mother of Heather Heyer, who was killed by a driver at the rally.
Bro ended with a touching speech about her daughter by announcing the launch of the Heather Heyer Foundation, a non-profit organization that offers scholarships to combat hatred.