Over the weekend, the actress and comedian shared a video with her Instagram followers saying that she underwent surgery to have her uterus and appendix removed.
"It's the morning after my surgery for endometriosis and my uterus is out," said Schumer in the video filmed from her hospital bed. "The doctor found 30 spots of endometriosis -- he removed my appendix because the endometriosis attacked it. There was a lot of blood in my uterus and I'm sore and I have some like gas pains."
According to the Mayo Clinic, endometriosis is an often painful disorder among women, where the endometrium, or tissue that normally lines the inside of the uterus, grows outside the uterus. The U.S. Office on Women's Health says endometriosis can also be found on other areas of the body, including the ovaries, fallopian tubes, vagina and cervix.
Endometriosis can sometimes cause severe pain, especially during menstrual periods, and can sometimes take years to diagnose.
Celebrities and Schumer's friends reached out to the star on Instagram and sent their love.
"LOVE YOU AMY!!!" wrote singer Elle King. "Sending healing vibes."
Chef Padma Lakshmi, who co-founded the nonprofit organization the Endometriosis Foundation of America, wrote, "Thank you so much for sharing your endo story. Over 200 million women worldwide suffer with this. Hope you feel better soon!"
Schumer, who is a mom to 2-year-old Gene David Fischer, has always been open about her fertility journey.
In January 2020, she told her followers she started the in vitro fertilization process to have another baby. Many people going through the same process related to the actress and shared their own stories.
"Your stories helped me more than you can imagine," Schumer wrote in an Instagram post. "I feel incredibly lucky."