Ask Dr. Marie: Less Frequent Pap Tests May Be Good for Women

Dr. Marie Savard says changing cervical cancer screening recs is a welcome step.

ByOPINION<br/>By MARIE SAVARD, M.D.<br>ABC News Medical Contributor
November 20, 2009, 12:43 PM

Nov. 20, 2009&#151; -- After the recent controversy over new breast cancer screening guidelines, the recommendations issued today by the American College of Obstetricians and Gynecologists (ACOG) to do fewer Pap tests to screen for cervical cancer may seem like another blow to women's health.

But the truth is, it isn't.

The new guidelines from the ACOG recommend the following:

Waiting to first test women with the Pap test until they are 21 will protect so many young women from unnecessary anxiety, biopsy of their cervix and potentially harmful treatment. We now know that most of these abnormal Pap tests in young women are caused by one of the many strains of the human papillomavirus and will go away on their own without treatment in one to two years.

Furthermore, and even more important, women who are aggressively treated for an abnormal Pap test have a much greater risk of premature birth and other pregnancy complications. I have cared for many women over the years who had prior cone biopsies and other treatments to their cervix which led to difficult pregnancies.

I am worried, however, that reducing the interval for Pap tests to every two to three years, depending on a woman's age, will lead to many women falling through the cracks of health care.

The annual Pap test has been an important part of women's health for so many years, and most women view the annual Pap test with the annual visit as a rite of passage each year. In truth, so much more goes on when a woman comes in for a regular checkup, including a breast, rectal and pelvic exam, along with a check of blood pressure, heart risk factors, and so much more.

I also wonder who will manage all of the Pap test results for women? Women frequently move and change doctors and practitioners. I worry that it will be difficult to know exactly which woman has had three negative Pap tests in a row unless a woman keeps those records for herself. As I have said over and over in the past, women should manage their own health records. They should give their practitioners a self-addressed stamped envelope at each visit and keep original copies of their test results. They can then make this information available to any future practitioner.

And, of course, I wonder how insurance companies will react to this. Almost certainly they will start covering fewer Pap tests, which makes sense. However, how will they know when a woman has had three negative Pap tests in a row -- or that a woman may have had an abnormal Pap test or positive HPV test or symptoms that need closer follow up?

A Little Background on Pap Tests

Until the Pap test was widely adopted in the United States in the late 1940s, cervical cancer was the number one cause of cancer death in women. After the widespread use of the Pap test, however, cervical cancer cases dropped by 70 percent. This is a huge success story.

(By the way, cervical cancer remains the number two cause of death worldwide -- and in very poor countries it tops the list of deadly cancers, as many countries cannot afford the costs associated with Pap tests.)

By 1999, the World Health Organization concluded that there was a single cause of cervical cancer -- the human papillomavirus. HPV is a simple double strand of DNA enclosed in a protein capsule that resembles a soccer ball when viewed under a special microscope. Although there are over 100 types of HPV, only about 15 types are linked to cancer. These 15 types are commonly called "high-risk strains" of the virus.

Soon after the discovery of HPV as the cause of cervical cancer, a DNA test to look for the high-risk strains of HPV was developed. This simple test is done using the same scraping of cells used for the Pap test. Although most women are exposed to HPV at some point in their lives -- which is why we suggest that all women undergo cervical cancer screening -- most women will fight off the virus within a year or two, and the virus either disappears altogether or remains dormant. Only about 5 percent of women will not fight off the virus, and these women will continue to test positive with the HPV test and may eventually develop precancerous cell changes -- and even cancer -- if these cell changes aren't treated.

The Pap test looks for cell changes under the microscope caused by the virus and is not foolproof. On occasion, the cell changes are not discovered and cervical cancer is eventually discovered. One of my sisters was diagnosed with cervical cancer earlier this year despite previously normal Pap tests. On the other hand, there are other causes of a mildly abnormal Pap test besides HPV, such as low estrogen in women after menopause. I had an abnormal Pap test after menopause which was from low estrogen and not from HPV.

Pap Tests: What Women Should Do

Here is a quick review of what I would recommend:

As always, I welcome your thoughts and suggestions.

Dr. Marie Savard is an ABC News medical contributor and author of "Ask Dr. Marie: Straight Talk and Reassuring Answers to Your Most Private Questions."

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