Survey: 7 Deaths From Anesthesia Drug Shortage

Survey Provides Glimpse Into Growing Patient Threat

ByABC News
April 12, 2012, 10:36 AM

April 16, 2012— -- Seven U.S. anesthesiologists have reported that drug shortages resulted in deaths of their patients, according to a new survey from the American Society of Anesthesiologists.

Although the online survey completed by 3,063 of the organization's 28,000 practicing anesthesiologists cannot be considered scientific, it opens a window to the growing shortage of anesthetics and painkillers used before, during and after surgery, and the potentially fatal consequences when those are unavailable.

Seven doctors responded to the question "How has a drug shortage impacted your patients?" by checking the option, "Has resulted in death of a patient," according to survey results exclusively obtained by

"We have a warning here. We are bound to trace this warning down and find out the extent of it," American Society of Anesthesiologists President Dr. Jerry A. Cohen said in an interview. "Are these the canary in the mine? I don't know. I worry that they are."

Because the survey was anonymous, Cohen said he couldn't determine where the reported deaths occurred, how the patients died, or be sure all seven reports were reliable. "Six we're absolutely sure were reported," Cohen said.

ASA had questions about "data points" in one responder's answers that cast doubts on one of the death reports, he explained. "It's unusual to have anybody report a death due to a drug shortage," Cohen said.

Responses to a similar ASA survey in 2011 included two reports of patient deaths, but those weren't made public, Katherine Looze, an ASA spokeswoman, revealed in response to a question from the ABC News Medical Unit.

Going forward with surgeries when they're short of needed drugs can put anesthesiologists in a legal bind, Cohen said. "We are at risk," he added. "If I proceed, if I don't have the drug I need -- and know I don't have the drug I need -- and I have a bad outcome, I'm responsible."

Among survey respondents (3,033 Americans and 30 from abroad), 97.6 percent reported being currently short of at least one drug and 96 percent said shortages forced them to use substitutes for particular patients and procedures. When they used alternatives to their top-choice drugs, some of their patients experienced nausea and vomiting, spent longer in surgery or took longer to recover from sedation or anesthesia, the survey revealed.

The drugs survey respondents most often couldn't get were the workhorses of local and general anesthesia, such as propofol, a milky white intravenous sedative and anesthetic that works in just 40 seconds. It's best known as the drug that led to the death of pop superstar Michael Jackson. Another is succinylcholine, a quick-acting paralytic agent frequently given to help insert a breathing tube into a patient's airway. There's also fentanyl, a powerful synthetic opioid used to knock patients out and to treat operative and post-op pain.

Anesthesiologists also reported problems getting thiopental, also known as sodium penthothal, an ultra-short acting barbiturate that's used less frequently today in hospitals, but remains in demand for the lethal cocktail many states use in executions. The shortage has left some prisoners longer on death row.