COVID-19 updates: Anti-vaccine protesters halt vaccinations at Dodger Stadium

Demonstrators carrying anti-mask and anti-vaccine signs blocked the entrance.

Last Updated: January 25, 2021, 11:22 AM EST

A pandemic of the novel coronavirus has now infected more than 102.5 million people worldwide and killed over 2.2 million of them, according to real-time data compiled by the Center for Systems Science and Engineering at Johns Hopkins University.

Latest headlines:

Here's how the news is developing today. All times Eastern.
Jan 25, 2021, 11:22 AM EST

Moderna says its COVID-19 vaccine is expected to protect against new variants

Laboratory experiments that tested Moderna's COVID-19 vaccine against new variants of the novel coronavirus show little to no impact on its efficacy, according to a press release from the company.

The vaccine produced antibodies that neutralized all key emerging variants tested, including B117 and B1351, which were first identified in the United Kingdom and in South Africa, respectively. The study showed "no significant impact" on neutralizing titers against the B117 variant. Meanwhile, a six-fold reduction in neutralizing titers was observed with the B1351 variant but remain above levels that are expected to be protective, according to the press release.

A vial labeled "Vaccine COVID-19" is seen next to Moderna's company logo on Nov. 18, 2020.
Joel Saget/AFP via Getty Images

Although the two-dose regimen of the vaccine is expected to be protective against emerging strains to date, Moderna announced Monday that it will test two additional strategies: one to explore whether adding an extra dose could offer more protection, and another to study a version of their original vaccine that's more tailored to the South Africa variant.

"As we seek to defeat the COVID-19 virus, which has created a worldwide pandemic, we believe it is imperative to be proactive as the virus evolves. We are encouraged by these new data, which reinforce our confidence that the Moderna COVID-19 Vaccine should be protective against these newly detected variants," Moderna CEO Stephane Bancel said in a statement. "Out of an abundance of caution and leveraging the flexibility of our mRNA platform, we are advancing an emerging variant booster candidate against the variant first identified in the Republic of South Africa into the clinic to determine if it will be more effective to boost titers against this and potentially future variants."

ABC News' Sony Salzman contributed to this report.

Jan 25, 2021, 10:34 AM EST

France's Pasteur Institute abandons vaccine candidate after disappointing results

France's world-renowned Pasteur Institute announced Monday that it is stopping development of one of its COVID-19 vaccine candidates, after finding the shot to be less effective than hoped.

The vaccine candidate, based on an existing measles vaccine, was being developed with American pharmaceutical company Merck and was put into phase 1 clinical trials last August. A review of interim results from the trials showed the shot "was well tolerated but produced immune responses that were inferior to those observed in people who had recovered naturally and to those observed in the authorized vaccines," according to a statement from the Pasteur Institute, which is located in Paris and is named after French scientist Louis Pasteur who created successful vaccines against rabies and anthrax in the 19th century.

PHOTO: Laboratory technicians work on the genome sequencing of SARS-CoV-2 and its variants at the National Reference Center (CNR) for Respiratory Infections Viruses of the Pasteur Institute in Paris, France, on Jan. 21, 2021.
Laboratory technicians wearing personal protective equipment work on the genome sequencing of SARS-CoV-2 and its variants at the National Reference Center (CNR) for Respiratory Infections Viruses of the Pasteur Institute in Paris, France, on Jan. 21, 2021.
Christophe Archambault/AFP via Getty Images

The decision to abandon development of the drug does not have any impact on the institute's continued research of two other prospective vaccines, which are "based on different methodologies" and are not yet ready for clinical trials, according to the statement.

"The Pasteur Institute will continue to develop other vaccine candidates that have reached the end of the preclinical phase, and maintain its strong scientific mobilization to fight the COVID-19 epidemic," the institute said.

ABC News' Ibtissem Guenfoud contributed to this report.

Jan 25, 2021, 8:56 AM EST

Fauci says he believes UK variant is indeed more virulent

Dr. Anthony Fauci, the top infectious disease expert in the United States, said he believes a new, more contagious variant of the novel coronavirus that was first detected in the United Kingdom is also more virulent.

When British scientists first studied the mutation "intensively" on a case-by-case basis, Fauci said they initially thought the variant was more transmissible but not necessarily more likely to cause serious illness or death.

"When they went and became more gradual and looked at the data, they became convinced that it is in fact a bit more virulent, namely making it more difficult when you get to the point of serious disease and even death. So I believe their data. I haven't seen all of it, but from what I've heard I believe the data," Fauci, director of the National Institute of Allergy and Infectious Diseases, told ABC News chief anchor George Stephanopoulos in an interview Monday on "Good Morning America."

ABC News has learned that U.S. President Joe Biden plans to impose a ban on most non-U.S. citizens entering the country who have recently been in South Africa as well as reinstate an entry ban on almost all non-U.S. citizens from Brazil, Ireland, the United Kingdom and 26 other European nations that allow travel across open borders. The move comes as a new, more contagious variants of the novel coronavirus have emerged out of South Africa, Brazil and the U.K. Some researchers worry that the mutations could reduce the potency of the two COVID-19 vaccines currently being used in the U.S.

Fauci, who is Biden's chief medical adviser, said he believes the South Africa travel ban was "prudent" and "the right decision," though he admitted "there's always a possibility and even a likelihood of some slippage."

"Right now, even though our surveillance isn't as comprehensive as we'd like it to be yet, it doesn't appear that this particular mutant is in the United States -- although it well may be," he said. "But if you have a free inflow of people from a country in which that mutant is clearly dominant -- I talk to my colleagues often in South Africa, it clearly is dominant there -- I believe the travel ban will be important, in addition to having a situation where anybody coming into the country now is going to be required to have a negative test before they even get on the plane, when they land to have a degree of quarantine as well as another test.

Fauci expressed hope that the vaccine shortages and delays in many communities across the U.S. will be corrected "within a very reasonable period of time," while cautioning, "it's going to take a little time."

"We've got to pull out all the stops," he said. "We've got to get into the trenches and figure out exactly at that local level what's going on and how to fix it."

He said "getting the vaccine situation on track" is Biden's "highest priority."

"The president has said it publicly, but in a private session, just sitting down with him and with the medical team, he's very serious. He said: 'Science is going to rule. We're going to go by the facts. We're going to go by the evidence. We're going to go by the data,'" Fauci recalled. "So the idea that the president himself sits down with you, says, 'I want science to rule, go out there and do everything we need to do to get it done,' just is really very refreshing."

Jan 25, 2021, 8:16 AM EST

Biden to impose South Africa travel ban and reinstate restrictions on Brazil, much of Europe

U.S. President Joe Biden will impose a ban on most non-U.S. citizens entering the country who have recently been in South Africa as well as reinstate an entry ban on almost all non-U.S. citizens from Brazil, Ireland, the United Kingdom and 26 other European nations that allow travel across open borders, a White House official told ABC News.

The new restrictions are expected to go into effect on Saturday, the official said.

Reuters was first to report the news.

U.S. President Joe Biden signs executive orders in the Oval Office of the White House in Washington, D.C., on Jan. 20, 2021, after his inauguration as the 46th president of the United States.
Tom Brenner/Reuters

The move comes as a new, more contagious variants of the novel coronavirus have emerged out of South Africa, Brazil and the U.K. Some researchers worry that the mutations could reduce the potency of the two COVID-19 vaccines currently being used in the U.S.

ABC News' Molly Nagle contributed to this report.

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