COVID-19 live updates: City sees fourfold increase in pediatric hospitalizations

The shift reflects the spread of the omicron variant.

Last Updated: December 27, 2021, 2:21 AM EST

As the COVID-19 pandemic has swept the globe, more than 5.3 million people have died from the disease worldwide, including over 816,000 Americans, according to real-time data compiled by Johns Hopkins University's Center for Systems Science and Engineering.

About 61.7% of the population in the United States is fully vaccinated against COVID-19, according to data from the Centers for Disease Control and Prevention.

Dec 23, 2021, 12:27 PM EST

UK reports 120,000 cases -- a record high

The United Kingdom recorded 119,789 COVID-19 cases in the past 24 hours, the highest number ever reported during the pandemic, according to official government data.

This brings the total number of infections over the past seven days to 678,165, which is an increase of 53.3% compared to last week.

It also marks the second consecutive day that cases of the virus have topped 100,000.

Deaths, comparatively, are not rising with the weekly total being 2.4% lower than the week before.

-ABC News’ Guy Davies

Dec 23, 2021, 12:14 PM EST

US stops shipment of 2 monoclonal antibody treatments

The U.S. government announced Thursday it is pausing shipment of two monoclonal antibody treatments because they are less effective against the omicron variant.

Eli Lilly’s and Regeneron’s treatments are not being sent to states after early data revealed they were not effective at preventing severe illness or hospitalization in patients infected with omicron.

The government will continue shipping sotrovimab, a monoclonal antibody treatment made by Vir Biotechnology and GlaxoSmithKline, which appears to combat the new variant.

In a statement, the Department of Health and Human Services said it is sending 55,000 doses of sotrovimab across the country and expects to distribute an additional 300,000 doses starting in January. 

Eli Lilly and Regeneron have said they are each developing updated versions of their monoclonal antibody treatments that will work against omicron. 

-ABC News’ Sony Salzman

Dec 23, 2021, 11:47 AM EST

Nearly 30,000 Americans have died of COVID since Thanksgiving

An ABC News analysis of federal data finds that nearly 30,000 Americans have died of COVID-19 since Thanksgiving as the omicron variant spreads across the country.

The U.S. is currently averaging more than 1,200 deaths per day, an increase of 23.3% in the last month with death rates up across almost all age groups.

Nationwide, about 161,000 new COVID cases are being reported every day, up nearly 75% in the last month.

This marks the highest daily case average since Labor Day, and means the U.S. will likely surpass the daily peaks seen during the delta-fueled wave over the summer.

Fourteen states, including New York, New Jersey, Illinois and Wisconsin, are reporting their highest daily case numbers in about a year.

-ABC News’ Arielle Mitropoulos

Dec 23, 2021, 10:41 AM EST

AstraZeneca monoclonal antibody works against omicron, studies show

New studies are offering additional reassurance that AstraZeneca's monoclonal antibody drug works against omicron.

The company's EVUSHELD retains neutralization activity against omicron, according to "live" virus neutralization data from both University College Oxford and Washington University School of Medicine.

AstraZeneca announced last week that its antibody drug would likely retain protection against omicron. These studies add to that growing evidence.

AstraZeneca's monoclonal antibody was authorized on Dec. 8, but for a narrow group of people. It is authorized as a way to prevent COVID-19 among people who are immune compromised, or people who are allergic to vaccine components. It is not authorized as a way to treat COVID-19 among people who have already tested positive.

There are three monoclonal antibody treatments currently authorized to treat people who already have COVID-19. Two of those treatments -- those made by Eli Lilly and Regeneron -- appear to have very little activity against omicron. A third treatment, made by Vir and GlaxoSmithKline, appears to work against omicron but is currently in short supply. The companies are working to scale up production.

-ABC News' Sony Salzman