Unvaccinated people 11 times more likely to die in COVID-19 delta surge

The unvaccinated were six times more likely to get the virus in August.

Last Updated: October 18, 2021, 1:16 AM EDT

The United States has been facing a COVID-19 surge as the more contagious delta variant continues to spread.

More than 722,000 Americans have died from COVID-19 while over 4.8 million people have died from the disease worldwide, according to real-time data compiled by the Center for Systems Science and Engineering at Johns Hopkins University.

Just 66.5% of Americans ages 12 and up are fully vaccinated against COVID-19, according to data from the CDC.

Latest headlines:

Here's how the news is developing. All times Eastern.
Oct 14, 2021, 2:03 PM EDT

Region sees hospitalizations at highest point in nearly 10 months

Alaska currently has the country's highest infection rate, followed by Montana, Wyoming, North Dakota, West Virginia and Idaho, according to federal data.

In the Department of Health and Human Services' Mountain Region – which includes Colorado, Montana, North Dakota, South Dakota, Utah and Wyoming -- hospital admissions are at their highest point in nearly 10 months, according to federal data.

Bismarck-Burleigh Public Health nurses Crys Kuntz, left, and Sara Nelson confer inside the Bismarck Event Center in Bismarck, N.D., where vehicles were lined up for the weekly drive-thru COVID-19 testing, Sept. 8, 2020.
Tom Stromme/The Bismarck Tribune via AP, FILE

A healthcare worker checks in patients arriving at the emergency room of Avera St. Luke's Hospital as the COVID-19 outbreak continues in Aberdeen, S.D., Oct. 26, 2020.
Bing Guan/Reuters, FILE

In the last five weeks, Michigan daily cases have nearly doubled and Minnesota daily cases have nearly tripled, according to federal data.

In New Hampshire and Vermont, daily cases are up by 40% and 43% respectively in the last month.

Over the last month, the U.S. has reported more than 47,000 confirmed COVID-19 deaths, including nearly 9,000 deaths recorded in the last week, according to federal data.

But hospital admissions have dropped by about 9.2% in the last week.

-ABC News' Arielle Mitropoulos

Oct 14, 2021, 1:33 PM EDT

Moderna says half dose booster will be just as effective

Dr. Jaqueline Miller, who presented data to the FDA committee on Thursday on behalf of Moderna, said the half dose works to boost antibody protections back up to the initial level.

"We chose the 50 microgram dose for the booster because we believe we should vaccinate with the lowest amount of antigen needed to induce an immune response at least equal to that in study 301 [the initial clinical study of Moderna vaccine], which was linked to vaccine efficacy of 93%," Miller said.

Miller added that "reducing the booster dose to 50 micrograms will also increase the worldwide vaccine supply of mRNA."

Americans who had a normal immune response to the first two shots and are getting a booster will need a half dose. But immunocompromised Americans -- people receiving cancer treatment or organ transplant recipients, for example -- need a full dose for their third shot to try and initiate the immune response they didn't get from the first two.

Moderna officials said they're preparing a letter explaining this administration to health care workers.

According to the FDA's review of Moderna's data, there was no evidence of increased side effects from booster doses.

-ABC News' Cheyenne Haslett

Oct 14, 2021, 1:07 PM EDT

Labor Department to issue new vaccine mandate

The U.S. is making progress in the fight against COVID-19 with daily cases and hospitalizations on the decline, but the nation must to do more to vaccinate Americans, President Joe Biden said Thursday.

President Joe Biden delivers an update on the COVID-19 response and vaccination program, in the South Court Auditorium on the White House campus, Oct. 14, 2021, in Washington, D.C.
Evan Vucci/AP

The Labor Department will soon issue a vaccine mandate for workplaces with 100 or more employees, Biden said.

Biden called on more businesses to "step up" and more parents to get their children vaccinated when eligible.

"We can't let up now," he said.

Oct 14, 2021, 11:54 AM EDT

FDA's independent committee hours away from vote on Moderna booster

The FDA's independent committee is meeting on Thursday and will vote in hours on whether to greenlight the Moderna booster for: people 65 and older; people 18 and older who are at high risk of severe illness because of an underlying health condition; and people 18 and older whose job may put them at greater risk for exposure to the virus.

A registered nurse applies a dose of the Moderna COVID-19 vaccine to Sarasota Hospital patient technician Carol Garcia at the Sarasota Memorial Hospital in Sarasota, Fla., Sept. 24, 2021.
Shannon Stapleton/Reuters, FILE

In introductory remarks Thursday, the FDA's Peter Marks urged the independent panel to "harmonize" its decision with what has already been decided for Pfizer in order to avoid unnecessary confusion for the public. 

Pfizer boosters have been authorized for people over 65, all adults with underlying medical conditions and adults whose job puts them at high risk. 

The vote is scheduled for about 4:45 p.m.

-ABC News' Sasha Pezenik