COVID-19 updates: Pfizer vaccine highly effective in children 5-11

About 64.3 million Americans ages 12 and older are completely unvaccinated.

ByJulia Jacobo, Ivan Pereira, Emily Shapiro, and Meredith Deliso
Last Updated: October 25, 2021, 2:03 AM EDT

More than 731,000 Americans have died from COVID-19 while over 4.9 million people have died from the disease worldwide, according to real-time data compiled by the Center for Systems Science and Engineering at Johns Hopkins University.

Just 66.9% of Americans ages 12 and up are fully vaccinated against COVID-19, according to data from the Centers for Disease Control and Prevention.

Latest headlines:

Here's how the news developed. All times Eastern.
Oct 20, 2021, 8:08 AM EDT

NYC to mandate vaccine for municipal workers

New York City Mayor Bill de Blasio on Wednesday announced a COVID-19 vaccine mandate for all municipal workers.

The mandate is expected to include all employees from sanitation workers to office workers and will require some 161,000 workers to have their first dose by Oct. 29.

Municipal employees who do not get vaccinated will be placed on unpaid leave, and their future employment will be resolved in negotiations with individual labor unions.

Correction officers will face a later deadline of Dec. 1.

-ABC News' Aaron Katersky

Oct 19, 2021, 2:56 PM EDT

Secretary Mayorkas tests positive for COVID-19

Department of Homeland Security Secretary Alejandro Mayorkas has tested positive for COVID-19, a DHS spokeswoman confirmed to ABC News. 

Mayorkas, who is fully vaccinated, "is experiencing only mild congestion," a statement said.

Secretary of Homeland Security Alejandro Mayorkas looks on during a conference at SRE Building, Oct. 8, 2021, in Mexico City, Mexico.
Hector Vivas/Getty Images

Mayorkas will work from home, the statement said. Contact tracing is underway.

There were no major White House officials deemed to be close contacts. "No White House principal has been determined to be a close contact of Secretary Mayorkas, given that the most recent contact was at the outdoor National Peace Officers’ Memorial Service, which took place outside of the 48-hour close contact window,” the White House said in a statement.

-ABC News' Luke Barr

Oct 19, 2021, 1:00 PM EDT

Pfizer vaccine 93% effective against hospitalizations for 12-18 age group

A new CDC study found that the Pfizer vaccine was 93% effective against hospitalizations for adolescents ages 12 to 18 from July to September.

The researchers also found that nearly all (97%) of adolescents ages 12 to 18 who were hospitalized with COVID-19 were unvaccinated. 

-ABC News' Sony Salzman

Oct 19, 2021, 12:30 PM EDT

10 states see rise in hospital admissions

Ten states -- all of which have colder temperatures -- have seen upticks in hospital admissions in recent weeks, according to federal data: Alaska, Colorado, Maine, Michigan, Minnesota, New Hampshire, North Dakota, Pennsylvania, Vermont and Wyoming.

However, nationwide, just under 58,000 Americans remain hospitalized, a major drop from 104,000 patients at the end of the summer, according to federal data.

An ambulance is seen outside the Erie County Medical Center (ECMC) Hospital in Buffalo, New York, Sept. 28, 2021.
Lindsay Dedario/Reuters, FILE

Death rates remain high, with more than 1,000 Americans dying each day, according to federal data.

Over the last month, the U.S. has reported approximately 45,000 COVID-19 deaths, including nearly 7,600 deaths in the last week.

-ABC News' Arielle Mitropoulos

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