Netanyahu also issued warnings to Iran and the entire Middle East.
Israel and Hezbollah are exchanging hundreds of cross-border strikes in the wake of the shocking explosions of wireless devices across Lebanon last week.
The Israel Defense Forces said Wednesday it was again "conducting extensive strikes in southern Lebanon and the Bekaa area" to the east of Beirut.
Almost 600 people -- including at least 50 children -- have been killed by Israeli strikes across Lebanon since Monday, according to the Lebanese Ministry of Public Health.
-ABC News Jordana Miller, Ghazi Balkiz and Joe Simonetti
Hezbollah claimed the launch of a Qadir-1 ballistic missile targeting the Mossad intelligence agency's headquarters on the outskirts of Tel Aviv on Wednesday morning.
"It is the headquarters responsible for the assassination of leaders and the bombing of pagers and hand-held radios," the militant group said in a statement, referring to last week's communication device explosions in Lebanon and Syria.
Sirens sounded in Tel Aviv amid the attack. "One surface-to-surface missile was identified crossing from Lebanon and was intercepted," the Israel Defense Forces said in a statement.
The IDF later said in a social media post that it destroyed the launcher from which the missile was fired in southern Lebanon.
The launch at Tel Aviv is the first time Hezbollah has attacked the city in central Israel since the war in the Gaza Strip began on Oct. 7.
-ABC News' Jordana Miller, Ghazi Balkiz, Jason Volack and Joe Simonetti
Hezbollah has confirmed the death of rocket and missile division commander Ibrahim Qubaisi in a post on their Telegram channel.
Hezbollah said he was killed in southern Lebanon.
Earlier Tuesday, the Israel Defense Forces said an Israeli air attack in Da'ahia in Beirut killed Qubaisi.
-ABC News' Ellie Kaufman
Israeli forces targeted eight residential homes in the Gaza Strip over the past 24 hours, killing at least 52 people, spokesperson Major Mahmoud Basal of the Hamas-run Gaza Civil Defense said Tuesday.
At least five of those people were killed after a house in the town of Al-Nasr, northeast of Rafah, was targeted, the civil defense spokesperson added.
The IDF said they were conducting "precise, intelligence-based operations in the Rafah area" in a statement Tuesday.
-ABC News' Sami Zyara and Jordana Miller
