Israel-Gaza updates: 22, including 18 children, reported dead in Rafah strikes

The Israel Defense Forces Aerial Defense Array successfully intercepted the majority of Iran's surface-to-surface missile launches using the "Arrow" Aerial Defense System, together with Israel's strategic allies, before the launches crossed into Israeli territory.

A small number of hits were identified, including at an IDF base in southern Israel, where minor damage was caused to infrastructure.

Over the past few hours, many dozens of hostile aircraft, as well as dozens of cruise missiles, from Iran were identified approaching Israeli territory and intercepted. Dozens of IAF fighter jets are currently operating to intercept all aerial threats approaching Israeli territory.

According to a situation analysis by IDF’s Home Front Command, the residents of the following towns: Northern Golan, Nevatim, Dimona, Eilat-City, Be'er Sheva and Arad no longer need to stay near a protected space.

The IDF said it is deployed on all fronts, prepared, and continuing to defend Israeli territory.

-ABC News' Will Gretsky

The U.S. helped "Israel take down nearly all of the incoming drones and missiles," President Joe Biden said in a statement late Saturday evening.

The president also detailed his call with Israeli Prime Minister Benjamin Netanyahu following the attacks, where Biden said he reaffirmed America's "ironclad commitment to the security of Israel." He also said that his team would stay in "close touch" with Israel's leaders.

Biden said his team will engage with the G7 leaders on Sunday to coordinate a "united diplomatic response to Iran’s brazen attack."

He noted that though American forces were not impacted, forces will continue to monitor and "will not hesitate to take all necessary action to protect our people."
-ABC News' Michelle Stoddart

According to Israeli police, Magen David Adom EMTs and paramedics were dispatched to 31 casualties in mild condition with anxiety symptoms or injuries caused while seeking shelter.

-ABC News' Will Gretsky

Congressional members from both sides of the aisle are out in full force expressing their full support for Israel and its right to defend itself from strikes by Iran.

Republicans are also calling on President Joe Biden to do more to assist Israel and to get tougher on Iran.

Senate Republican Leader Mitch McConnell, in a particularly strongly-worded statement, called on the administration to "lead an international effort to impose sufficient costs on Tehran to compel an end to its aggression and terror, both on Israeli soil and -- as demonstrated with today’s IRGC assault on a commercial shipping vessel -- around the region."

Congress has not yet approved additional aid to Israel specific to the escalating conflict in the region since Hamas' Oct. 7 attack.

The Senate approved billions in aid for Israel as part of its national defense supplemental, including aid for Ukraine. The House has not taken it up, and House Speaker Mike Johnson has instead said he's working on crafting yet-to-be-announced modifications to that package.

In a statement Saturday night, House Majority Leader Steve Scalise said the House will "move from its previously announced legislative schedule next week to instead consider legislation that supports our ally Israel and holds Iran and its terrorist proxies accountable."

-ABC News' Allison Pecorin and John Parkinson