Israel-Gaza-Lebanon updates: Iranian president responds to Israel's retaliation

The Israel Defense Forces arrested 44 male staff members from the Kamal Adwan Hospital, leaving behind the hospital director, one male doctor and female staff to care for 200 patients, according to the World Health Organization.

"The situation in northern Gaza is catastrophic. Intensive military operations unfolding around and within healthcare facilities and a critical shortage of medical supplies, compounded by severely limited access, are depriving people of life saving care," the WHO said in a statement Saturday.

"The Health Ministry in Gaza informed us that the siege at Kamal Adwan Hospital has ended, but it came at a heavy cost," the WHO said. "Reports of the hospital facilities and medical supplies being damaged or destroyed during the siege are deplorable."

The IDF's raid of the Kamal Adwan Hospital, in North Gaza, left behind a path of destruction, according to videos.

Civilians taking shelter at the hospital were told to go to the courtyard. Women and children were separated from the men, witnesses told local journalists. One journalist who was in the hospital told other local journalists he was detained and taken with others to an area in Beit Lahia where he says he was beaten before being released and told to go south.

MedGlobal, a U.S. charity which is affiliated with the hospital, released a statement condemning the detention of the hospital's nursing director, Mahmoud Lubbad, in the raid. Dr. Hussam Abu Safiya, the director of the hospital, said goodbye to his teenage son on Saturday, who was killed overnight in Jabalia.

Cleared videos show debris in the courtyard, walls of neighboring buildings torn down and mangled ambulances. Bodies are in the courtyard have been wrapped in shrouds.

A "substantial" part of Israel’s attack on Iran originated from jets outside Iranian airspace, two Israeli officials told ABC News.

It remains unclear if Iran will choose to retaliate, one Israeli security official said.

In a statement, The Israel Defense Forces said it had "completed precise and targeted strikes against military targets in a number of areas in Iran,” adding that “the mission was fulfilled” and Israeli aircraft have now “safely returned home."

The strikes were "conducted in response to the attacks by the Iranian regime against the State of Israel and its citizens in recent months," according to the IDF.

There were no reports of Israeli casualties nor damage to Israeli warplanes, an Israeli source with direct knowledge told ABC News.

-ABC News' Dana Savir, Matt Gutman, Bruno Nota and Jordana Miller

Iran’s Army published a statement saying two military personnel were killed in the Israeli attack on Iran.

"The army of the Islamic Republic of Iran sacrificed two of its soldiers last night while confronting the projectiles of the criminal Zionist regime in order to defend the security of Iran and prevent harm to the nation and the interests of Iran," the statement read.