Israel-Gaza updates: 300,000 have fled Rafah, UN agency says

UNICEF officials continued to raise an alarm over the humanitarian conditions in Gaza, saying people are "exhausted, terrified" and don't have access to proper sanitation facilities and warn that if aid is not allowed into Gaza in the next 48 hours conditions will deteriorate further.

"I have been working on large-scale humanitarian emergencies for the best part of the last 30 years and I've never been involved in a situation as devastating, complex or erratic as this," James Elder a spokesperson for UNICEF, said.

"When I arrived in Gaza in the middle of November, I was shocked by the severity of the impact of this conflict on children and, impossibly, it has continued to worsen since. Yesterday, I walked around Al-Mawasi, the so-called 'humanitarian zone’ that people in eastern Rafah are being told to move to. More than 100,000 people have fled Rafah in the last 5 days and the stream of displacement continues. The roads to Mawasi are jammed – many hundreds of trucks, buses, cars and donkey carts loaded with people and possessions," Elder said.

Food stock for people in the south is expected to run out on Saturday while lack of fuel means that hospital wards cannot function. Elder also warned that a ground offensive in Rafah will lead to the number of children dead increasing "dramatically," with 14,000 being killed already.

"For 5 days, no fuel and virtually no humanitarian aid entered the Gaza Strip and we are scraping the bottom of the barrel. This is already a huge issue for the population and for all humanitarian actors but in a matter of days, if not corrected, the lack of fuel could grind humanitarian operations to a halt," Elder said.

"At a time when people are being forced to pick up and move again, the lifesaving supplies that sustain and support them have been entirely cut off. Let’s be very clear – this will result in children dying. Deaths that can be prevented," Elder said.

-ABC News' Will Gretsky

Prime Minister Benjamin Netanyahu made it clear in a 46-minute interview with McGraw that Israel plans to proceed with its operation in Rafah.

McGraw interviewed Netanyahu from Jerusalem with a sweeping view of the city in the background on a streaming platform called Merit+.

Netanyahu said Israel has destroyed "20 battalions of Hamas' 24 terrorist battalions," and the final four are in Rafah.

"We’ve achieved, we’ve destroyed about 20 battalions of Hamas' 24 terrorist battalions, we have another four ... they're in Rafah, and that’s why we want to go into Rafah because we can’t leave them there," Netanyahu told McGraw.

Netanyahu also criticized students protesting on college campuses, saying their understanding of history goes "back to breakfast, at best."

"What is happening on American campuses and American cities, you got ... first of all, you have a lot of ignorant people there," Netanyahu said. "I'm sorry to say, whose sense of history at best goes back to breakfast. Not even that, OK? They don't have the faintest clue what Hamas is."

Netanyahu pointed to what he said were dangerous comments from American college presidents.

"When the president of the university is asked, well, what would you say if somebody calls for the genocide of Jews? And [they] say it depends on the context. No, it doesn't. No, it doesn't."

ABC News' Ellie Kaufman and Hajah Bah

Amid reports that cease-fire negotiations between Hamas and Israel have fallen through, the U.S. State Department is saying hope still remains for a deal. The State Department also refuted the notion that President Joe Biden's decision to halt some arms transfers to Israel — and his assertion that he will cut off additional shipments if the country invades Rafah — had weakened its position at the negotiating table.

"That is not at all our assessment of the hostage talks. We actually think that a Rafah operation would weaken Israel’s position both in these talks and writ large," State Department spokesperson Matt Miller said, arguing a major incursion would "further weaken Israel’s standing in the world."

Although the paused arm shipments won’t impact Israel’s readiness to conduct a major operation in Rafah, some U.S. officials who have long been skeptical that Hamas will ever agree to a deal that involves handing over all of the hostages say the group could interpret the move (and Biden’s public warning) as a compelling sign that support for Israel among its closest allies is beginning to crumble.

Despite the heightened tensions between the Biden administration and Benjamin Netanyahu’s government, Miller said the U.S. would continue to work with Israel in the hopes of reaching a deal.

"We continue to engage with the Israeli government on the amendments to the proposal that Hamas submitted earlier this week,” Miller said. “We continue to work to try to finalize the text, try to get an agreement. And I will just say that any effort like this is incredibly difficult. This one has certainly been incredibly difficult, but we will continue to stay engaged because we believe it's in the interest of all parties."

-ABC News' Shannon Crawford

Amid tensions between the U.S. and Israel over the invasion of Rafah, Israeli Prime Minister Benjamin Netanyahu said Israel will stand alone if it has to.

"Today we are much stronger. We are determined, and we are united to defeat our enemy and those who seek our souls. If we have to stand alone, we will stand alone," Netanyahu said in a statement Thursday.

"I already said that if we have to - we will fight tooth and nail," Netanyahu said.