Clinton and Trump engaged in 90 minutes of nonstop debating, moderated by "NBC Nightly News" anchor Lester Holt, to make their case to American voters for why they should occupy the White House.
Here are the most memorable lines of the debate:
"Now, in all fairness to Secretary Clinton, yes, is that OK? Good. I want you to be very happy. It's very important to me."
"That's called business, by the way."
"Donald, I know you live in your own reality."
"You're telling the enemy everything you want to do. No wonder you've been fighting ISIS your entire adult life."
"I have a feeling by the end of this evening, I'm going to be blamed for everything that's ever happened."
"When she releases her 33,000 e-mails that have been deleted, as soon as she releases her 33,000 e-mails, I will release my tax returns."
"I can only say that I'm certainly relieved that my late father never did business with you."
"No. You're wrong."
"I was the one that got him to produce the birth certificate, and I think I did a good job."
"It also could be somebody sitting on their bed that weighs 400 pounds, OK?"
"I hope the fact-checkers are turning up the volume and really working hard. Donald supported the invasion of Iraq."
"The record shows otherwise."
"That line's getting a little bit old. I must say."
"She doesn't have the look. She doesn’t have the stamina. I said she doesn't have the stamina, and I don't believe she does have the stamina. To be president of this country, you need tremendous stamina."
"As soon as he travels to 112 countries and negotiates a peace deal, a cease-fire, a release of dissidents, an opening of new opportunities and nations around the world or even spends 11 hours testifying in front of a congressional committee, he can talk to me about stamina."
"I certainly will support the outcome of this election."
"If she wins, I will absolutely support her."
Clinton and Trump, respectively, answer the debate's final question: Will the candidates accept the results of the election as the will of the voters?