It's an achievement the former secretary of state has called "emotional." When The Associated Press declared that she had reached the magic number of needed delegates on Monday night, she told a crowd of supporters in California, "We are in the brink of a historic, historic, unprecedented moment."
Clinton took a few swipes at the Republican presumptive nominee, Donald Trump, calling him "temperamentally unfit" to be president.
"When he says, 'Let's make America great again,' that is code for 'Let's take America backwards,'" she said.
And in an emotional tribute to her late mother, Clinton talked very personally about how it felt to be the presumptive nominee.
"On the very day my mother was born, in Chicago, Congress was passing the 19th Amendment to the Constitution. That amendment finally gave women the right to vote," Clinton said as the crowd danced and cheered, adding, "I wish she could see her daughter become the Democratic Party's nominee."
Clinton first acknowledged her status as the Democratic presumptive nominee in a fundraising email sent before her victory speech.
"After all our hard work and tough fights — and an unwavering commitment to love, kindness, our country and each other — we broke one of the highest, hardest glass ceilings in America," the email reads.
"For the first time ever, a woman will be a major party's nominee to become president of the United States," it states.
"Although we weren't able to shatter that highest, hardest glass ceiling this time," she said during her concession remarks then, "thanks to you, it has about 18 million cracks in it."
Tuesday night, the Democratic presumptive nominee perhaps took the first step, congratulating Sanders for running an "extraordinary" campaign and calling for party solidarity.
"Whether you supported me or Sen. Sanders or one of the Republicans, we all need to keep working to a better, fairer, stronger America," Clinton told a crowd of nearly 4,000 supporters. "We believe that cooperation is better than conflict, unity is better than division, empowerment is better than resentment and bridges are better than walls."
The drawn out and at times volatile Democratic primary contest lasted longer than the Republican race — something few predicted. In the end, Clinton visited 42 states during the primaries and held 419 public events, according to a campaign official.